Maider Zabala
1. Position in the laboratory
Instructor
mzabala@stanford.edu
2. Previous affiliations:
- Postdoctoral fellow at Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University
- Ph.D. in Hepatology and Gene Therapy. University of Navarra, Pamplona (Spain)
3. Current Projects:
Identification of novel microRNAs involved in self-renewal and differentiation of the mammary gland
4. Interesting facts and hobbies:
Listen to music and people gathered in a bar; eating and cooking (I can also listen to people at the same time); travel; beach, sun and fashion!
5. Publications:
Zabala M, Juan R. Rodriguez-Madoz, Maite Alfaro, M. Gabriela Kramer and Cristian Smerdou “Short-term intratumoral IL-12 expressed from an alphaviral vector is sufficient to induce an efficient antitumoral response against spontaneous hepatocellular carcinomas”. Hum Gen Ther. 2014 Jan 7.
Parashurama N, Lobo NA, Ito K, Mosley AR, Habte FG, Zabala M, Smith BR, Lam J, Weissman IL, Clarke MF, Gambhir SS “Remodeling of endogenous mammary epithelium by breast cancer stem cells.” Stem Cells. 2012 Oct;30(10):2114-27
Dalerba P, Kalisky T, Sahoo D, Rajendran PS, Rothenberg ME, Leyrat AA, Sim S, Okamoto J, Johnston DM, Qian D, Zabala M, Bueno J, Neff NF, Wang J, Shelton AA, Visser B, Hisamori S, Shimono Y, van de Wetering M, Clevers H, Clarke MF, Quake SR. “Single-cell dissection of transcriptional heterogeneity in human colon tumors”. Nat Biotechnol. 2011 Nov 13;29(12):1120-7
Medina-Echeverz J, Fioravanti J, Zabala M, Ardaiz N, Prieto J, Berraondo P. “Successful colon cancer eradication after chemoimmunotherapy is associated with profound phenotypic change of intratumoral myeloid cells.” J Immunol. 2011 Jan 15;186(2):807-15.
Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, Diehn M, Liu H, Panula SP, Chiao E, Dirbas FM, Somlo G, Pera RA, Lao K, Clarke MF. “Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells”. Cell. 2009 Aug 7;138(3):592-603.
Zabala M, Alzuguren P, Benavides C, Crettaz J, Gonzalez-Aseguinolaza G, Ortiz de Solorzano C, Gonzalez-Aparicio M, Kramer MG, Prieto J, Hernandez-Alcoceba R (2009). “Evaluation of bioluminescent imaging for noninvasive monitoring of colorectal cancer progression in the liver and its response to immunogene therapy”. Mol Cancer. 2009 Jan 7;8:2.
Sivanandam VG, Stephen SL, Hernandez-Alcoceba R, Alzuguren P, Zabala M, van Rooijen N, Qian C, Berger I, Gross ML, Prieto J, Kochanek S. “Lethality in an anti-angiogenic tumor gene therapy model upon constitutive but not inducible expression of the soluble vascular endothelial growth factor receptor 1”. J Gene Med. 2008 Oct;10(10):1083-91.
Reboredo M, Zabala M, Mauleón I, de la Rivas J, Kreppel F, Kochanek S, Prieto J, Hernández-Alcoceba R and Kramer MG. “Interleukin-12 inhibits liver-specific drug-inducible systems in vivo”. Gene Ther. 2008 Feb;15(4):277-88
Zabala M, Lasarte JJ, Perret C, Sola J, Larrea E, Prieto J and Kramer MG. “Induction of immunosuppresiive molecules and regulatory T cells counteracts the antitumor effect of interleukin-12-based gene therapy in a transgenic mouse model of liver cancer”. J Hepatol. 2007 Dec;47(6):807-15
Zabala M, Wang L, Hernandez-Alcoceba R, Hillen W, Qian C, Prieto J, Kramer MG. “Optimization of the Tet-on system to regulate interleukin 12 expression in the liver for the treatment of hepatic tumors”. Cancer Res. 2004 Apr 15; 64(8):2799-804
Ruz N, Zabala M, Kramer MG, Campanero MA, Dios-Vieitez MC, Blanco-Prieto MJ. “Rapid and simple determination of doxycycline in serum by high-performance liquid chromatography: Application to particulate drug delivery systems”. J Chromatogr A. 2004 Mar 26; 1031(1-2):295-301.
Wang L, Hernandez-Alcoceba R, Shankar V, Zabala M, Kochanek S, Sangro B, Kramer MG, Prieto J, Qian C. (2004). “Prolonged and inducible transgene expression in the liver using gutless adenovirus: a potential therapy for liver cancer”. Gastroenterology. 2004 Jan; 126(1):278-89.
