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Tushar Desai
Pulmonologist
Practice Areas
Professional Education
- Medical Education: Tufts University (1995) MA
- Internship: University of Michigan Medical Center (1996) MI
- Residency: University of Michigan Medical Center (1998) MI
- Board Certification: Pulmonary Disease, American Board of Internal Medicine (2001)
- Fellowship: Boston University School of Medicine (2002) MA
- BA, Amherst College, Psychology (1991)
- MD, MPH, Tufts University School of Medicine, Medicine, Public Health (1995)
Honors & Awards
- Worth F. Bloom M25 Prize, Tufts University School of Medicine (1995)
- House Officer Research Award, University of Michigan Hospitals, Department of Internal Medicine (1998)
- Robert Dawson Evans Fellow Excellence in Teaching Award, Boston University School of Medicine, Department of Internal Medicine (2000)
- Retinoic Acid in Early Lung Morphogenesis, GlaxoSmithKline Pulmonary Fellowship Award (2002-2003)
- Fellowship in Pulmonary Research, Parker B. Francis Foundation (2006-2009)
- Development and Maintenance of the Alveolar Type 1 Cell (K08), NIH/NHLBI (2008-2013)
- ITI Faculty Seed Grant 2014, Stanford Institute for Immunity, Transplantation, and Infection (2014-2015)
- Interrogation of Individual Cells to Identify Progenitor Cells and Their Niches (U01), NIH/NHLBI (2014-2016)
- In Situ Transcriptome Profiling in Histological Sections, Stanford Bio-X Interdisciplinary Initiatives Program 2014 (2014-2016)
- Selective Aging of the Lungs: Using Conditional Klotho Deletion to Identify the Basis for Emphysema, Glenn Center for the Biology of Aging Seed Grant 2014 (2015-2017)
- A Genetic Dissection of Lung Adenoma Initiation and Progression, American Lung Association, Lung Cancer Discovery Award (2015-2017)
Publications
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Keeping it together: Pulmonary alveoli are maintained by a hierarchy of cellular programs.
Logan, C. Y., & Desai, T. J. (2015). Keeping it together: Pulmonary alveoli are maintained by a hierarchy of cellular programs. BioEssays , 37(9), 1028-1037. -
Cellular mechanisms of alveolar pathology in childhood interstitial lung diseases: current insights from mouse genetics
Kuo, C. S., & Desai, T. J. (2015). Cellular mechanisms of alveolar pathology in childhood interstitial lung diseases: current insights from mouse genetics. CURRENT OPINION IN PEDIATRICS, 27(3), 341-347. -
Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq.
Treutlein, B., Brownfield, D. G., Wu, A. R., Neff, N. F., Mantalas, G. L., & Quake, S. R. (2014). Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq. Nature, 509(7500), 371-375. -
Alveolar progenitor and stem cells in lung development, renewal and cancer
Desai, T. J., Brownfield, D. G., & Krasnow, M. A. (2014). Alveolar progenitor and stem cells in lung development, renewal and cancer. NATURE, 507(7491), 190-?.
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Stem cells: Differentiated cells in a back-up role.
Desai, T. J., & Krasnow, M. A. (2013). Stem cells: Differentiated cells in a back-up role. Nature, 503(7475), 204-205.
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Smooth muscle protein 22 alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling
El-Bizri, N., Wang, L., Merklinger, S. L., Guignabert, C., Desai, T., & Rabinovitch, M. (2008). Smooth muscle protein 22 alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling. CIRCULATION RESEARCH, 102(3), 380-388.
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In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses
Grimm D, Lee JS, Wang L, Desai T, Akache B, & Kay MA. (2008). In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses. J Virol, 82(12).
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Inhibition of Tgf beta signaling by endogenous retinoic acid is essential for primary lung bud induction
Chen, F., Desai, T. J., Qian, J., Niederreither, K., Lu, J., & Cardoso, W. V. (2007). Inhibition of Tgf beta signaling by endogenous retinoic acid is essential for primary lung bud induction. DEVELOPMENT, 134(16), 2969-2979.
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Distinct roles for retinoic acid receptors alpha and beta in early lung morphogenesis
Desai, T. J., Chen, F., Lu, J. M., Qian, J., Niederreither, K., & Cardoso, W. V. (2006). Distinct roles for retinoic acid receptors alpha and beta in early lung morphogenesis. DEVELOPMENTAL BIOLOGY, 291(1), 12-24.
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Retinoic acid selectively regulates Fgf10 expression and maintains cell identity in the prospective lung field of the developing foregut
Desai, T. J., Malpel, S., Flentke, G. R., Smith, S. M., & Cardoso, W. V. (2004). Retinoic acid selectively regulates Fgf10 expression and maintains cell identity in the prospective lung field of the developing foregut. DEVELOPMENTAL BIOLOGY, 273(2), 402-415.
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COPD: Clinical Manifestations, Diagnosis, and Treatment
Desai TJ, Karlinsky, & JB. (2004). COPD: Clinical Manifestations, Diagnosis, and Treatment. Baum's Textbook of Pulmonary Diseases (Eds: James D. Crapo, Jeffrey Glassroth, Joel Karlinsky, and Talmadge E. King Jr.), 7th ed.
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Growth factors in lung development and disease: friends or foe?
Desai, T. J., & Cardoso, W. V. (2002). Growth factors in lung development and disease: friends or foe?. Respiratory research, 3, 2-?.
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Participation of urokinase-type plasminogen activator receptor in the clearance of fibrin from the lung
Hattori, N., Sisson, T. H., Xu, Y., Desai, T. J., & Simon, R. H. (1999). Participation of urokinase-type plasminogen activator receptor in the clearance of fibrin from the lung. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 277(3), L573-L579.
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