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![](/was/20151211033644im_/https://stanfordhealthcare.org/content/dam/SHC/doctors-medicalstaff/n/nayak-jayakar-md.png/_jcr_content/renditions/cq5dam.thumbnail.319.319.png.transform/221x221/q82/image.png)
Jayakar V. Nayak, MD, PhD
Otolaryngologist, Endoscopic nasal and sinus surgeon, Rhinologist
Practice Areas
Professional Education
- Board Certification: Otolaryngology, American Board of Otolaryngology (2010)
- Fellowship: University of Pennsylvania (2009) PA
- Residency: University of Pittsburgh Medical Center (2008) PA
- Internship: University of Pittsburgh Medical Center (2004) PA
- M.D., Ph.D., University of Pittsburgh School of Medicine, MD - General Medicine PhD - Immunology (2003)
- Medical Education: University of Pittsburgh School of Medicine (2003) PA
- B.A., University of Pennsylvania, Neuroscience (1992)
Honors & Awards
- Co-Valedictorian, Woodbridge High School, New Jersey (1988)
- Baccalaureate with Honors, University of Pennsylvania (1992)
- Stanley J. Sarnoff Endowment Medical Student Research Fellowship, Salk Institute, La Jolla, CA (1994)
- Howard Hughes Medical Institute Medical Student Research Fellowship, U California, San Diego (1995)
- American Heart Association Medical Student Research Fellowship, U Californioa, San Diego (1996)
- M.D./Ph.D. Transfer Admission & Full Scholarship Award, University of Pittsburgh (1997)
- Bernhard A. Goldman Prize in Dermatology, University of Pittsburgh (2003)
- Gold Foundation Little Apple Medical Student Teaching Award Finalist, University of Pittsburgh (2004)
- CORE Schering Plough Resident Research Award from the American Academy of Otolaryngology, University of Pittsburgh (2005)
- Influenza virus tropism for human nasal epithelial cells of the upper airway, Marion Avery Family Grant (2012)
- 2D and 3D Electron Microscopy Ultrastructure of Murine Nasal Cavity, Stanford Beckman Center Technology Innovation MiniGrant program (2012)
- Immune Responses to Influenza Virus in Single Human Nasal Epithelial Cells, NIH/Cooperative Centers for Translational Research on Human Immunology and Biodefense (CCHI) (2012)
- Human Mucosal Immune Responses to Influenza Virus: a Systems Biology Approach, NIH/Human Immunology Project Consortium (HIPC) (2012)
- Career Development Award - Basal cells in maintenance and regeneration of the nasal epithelium, Triological Society of the American Academy of Otolaryngology-Head and Neck Surgery (2012)
- National Finalist - Clinical Scientist Development Award, Doris Duke Charitable Foundation (December 2014)
Publications
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Medical therapy vs surgery for recurrent acute rhinosinusitis.
Costa, M. L., Psaltis, A. J., Nayak, J. V., & Hwang, P. H. (2015). Medical therapy vs surgery for recurrent acute rhinosinusitis. International forum of allergy & rhinology, 5(8), 667-673. -
Endoscopic Transnasal Approach for Urgent Decompression of the Craniocervical Junction in Acute Skull Base Osteomyelitis.
Burns, T. C., Mindea, S. A., Pendharkar, A. V., Lapustea, N. B., Irime, I., & Nayak, J. V. (2015). Endoscopic Transnasal Approach for Urgent Decompression of the Craniocervical Junction in Acute Skull Base Osteomyelitis. Journal of neurological surgery reports, 76(1), e37-42. -
Intraocular Pressure Changes in Emergent Surgical Decompression of Orbital Compartment Syndrome
Mohammadi, F., Rashan, A., Psaltis, A., Janisewicz, A., Li, P., & Nayak, J. V. (2015). Intraocular Pressure Changes in Emergent Surgical Decompression of Orbital Compartment Syndrome. JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY, 141(6), 562-565. -
Clinical predictors of neo-osteogenesis in patients with chronic rhinosinusitis.
Huang, Z., Hajjij, A., Li, G., Nayak, J. V., Zhou, B., & Hwang, P. H. (2015). Clinical predictors of neo-osteogenesis in patients with chronic rhinosinusitis. International forum of allergy & rhinology, 5(4), 303-309.
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Consistent Ipsilateral Development of the Posterior Extension of the Quadrangular Cartilage and Bony Spur Formation in Nasal Septal Deviation
Saedi, B., Rashan, A. R., Lipan, M., Nayak, J. V., & Most, S. P. (2015). Consistent Ipsilateral Development of the Posterior Extension of the Quadrangular Cartilage and Bony Spur Formation in Nasal Septal Deviation. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 152(3), 444-448.
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Inverted Papilloma of the Sphenoid Sinus: Risk Factors for Disease Recurrence
Suh, J. D., Ramakrishnan, V. R., Thompson, C. F., Woodworth, B. A., Adappa, N. D., & Palmer, J. N. (2015). Inverted Papilloma of the Sphenoid Sinus: Risk Factors for Disease Recurrence. LARYNGOSCOPE, 125(3), 544-548.
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Complications Associated With the Pedicled Nasoseptal Flap for Skull Base Reconstruction
Soudry, E., Psaltis, A. J., Lee, K. H., Vaezafshar, R., Nayak, J. V., & Hwang, P. H. (2015). Complications Associated With the Pedicled Nasoseptal Flap for Skull Base Reconstruction. LARYNGOSCOPE, 125(1), 80-85.
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The Combined Subtemporal-Transfacial Approach for the Resection of Juvenile Nasopharyngeal Angiofibromas With Intracranial Extension
Kumar, A. R., Nayak, J. V., Janisiewicz, A. M., Li, G., & Oghalai, J. S. (2015). The Combined Subtemporal-Transfacial Approach for the Resection of Juvenile Nasopharyngeal Angiofibromas With Intracranial Extension. OTOLOGY & NEUROTOLOGY, 36(1), 151-155.
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Long-term outcomes of endoscopic maxillary mega-antrostomy for refractory chronic maxillary sinusitis.
Costa, M. L., Psaltis, A. J., Nayak, J. V., & Hwang, P. H. (2015). Long-term outcomes of endoscopic maxillary mega-antrostomy for refractory chronic maxillary sinusitis. International forum of allergy & rhinology, 5(1), 60-65.
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A case of stereotactic radiation in skull base solitary fibrous tumor: more harm than good?
Santa Maria, P. L., Abuzeid, W. M., Nayak, J. V., Chang, S. D., & Blevins, N. H. (2014). A case of stereotactic radiation in skull base solitary fibrous tumor: more harm than good?. Journal of neurological surgery reports, 75(2), e214-6.
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Air pollutants cause release of hydrogen peroxide and interleukin-8 in a human primary nasal tissue culture model.
Cho, D.-Y., Le, W., Bravo, D. T., Hwang, P. H., Illek, B., & Nayak, J. V. (2014). Air pollutants cause release of hydrogen peroxide and interleukin-8 in a human primary nasal tissue culture model. International forum of allergy & rhinology, 4(12), 966-971.
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Long-term Sinonasal Outcomes of Aspirin Desensitization in Aspirin Exacerbated Respiratory Disease
Cho, K.-S., Soudry, E., Psaltis, A. J., Nadeau, K. C., McGhee, S. A., & Hwang, P. H. (2014). Long-term Sinonasal Outcomes of Aspirin Desensitization in Aspirin Exacerbated Respiratory Disease. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 151(4), 575-581.
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Anatomic relationship of nasolacrimal duct and major lateral wall landmarks: cadaveric study with surgical implications
Ali, M. J., Nayak, J. V., Vaezeafshar, R., Li, G., & Psaltis, A. J. (2014). Anatomic relationship of nasolacrimal duct and major lateral wall landmarks: cadaveric study with surgical implications. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 4(8), 684-688.
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Outpatient endoscopic sinus surgery in cystic fibrosis patients: predictive factors for admission
Soudry, E., Mohabir, P. K., Miglani, A., Chen, J., Nayak, J. V., & Hwang, P. H. (2014). Outpatient endoscopic sinus surgery in cystic fibrosis patients: predictive factors for admission. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 4(5), 416-421.
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Endoscopic Reconstruction of Surgically Created Skull Base Defects A Systematic Review
Soudry, E., Turner, J. H., Nayak, J. V., & Hwang, P. H. (2014). Endoscopic Reconstruction of Surgically Created Skull Base Defects A Systematic Review. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 150(5), 730-738.
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Outpatient endoscopic sinus surgery in cystic fibrosis patients: predictive factors for admission.
Soudry, E., Mohabir, P. K., Miglani, A., Chen, J., Nayak, J. V., & Hwang, P. H. (2014). Outpatient endoscopic sinus surgery in cystic fibrosis patients: predictive factors for admission. International forum of allergy & rhinology, 4(5), 416-421.
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Experience with intraoperative navigation and imaging during endoscopic transnasal spinal approaches to the foramen magnum and odontoid.
Choudhri, O., Mindea, S. A., Feroze, A., Soudry, E., Chang, S. D., & Nayak, J. V. (2014). Experience with intraoperative navigation and imaging during endoscopic transnasal spinal approaches to the foramen magnum and odontoid. Neurosurgical focus, 36(3), E4-?.
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Human ethmoid sinus mucosa: a promising novel tissue source of mesenchymal progenitor cells
Cho, K.-S., Park, H.-Y., Roh, H.-J., Bravo, D. T., Hwang, P. H., & Nayak, J. V. (2014). Human ethmoid sinus mucosa: a promising novel tissue source of mesenchymal progenitor cells. STEM CELL RESEARCH & THERAPY, 5.
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Systemic prednisone administration selectively alters granulocyte subsets in nasal polyps from aspirin-exacerbated respiratory disease and chronic rhinosinusitis patients.
Edward, J. A., Sanyal, M., Ramakrishnan, V. R., Le, W., Nguyen, A. L., & Nayak, J. V. (2013). Systemic prednisone administration selectively alters granulocyte subsets in nasal polyps from aspirin-exacerbated respiratory disease and chronic rhinosinusitis patients. International forum of allergy & rhinology, 3(11), 866-876.
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Systemic prednisone administration selectively alters granulocyte subsets in nasal polyps from aspirin-exacerbated respiratory disease and chronic rhinosinusitis patients
Edward, J. A., Sanyal, M., Ramakrishnan, V. R., Le, W., Nguyen, A. L., & Nayak, J. V. (2013). Systemic prednisone administration selectively alters granulocyte subsets in nasal polyps from aspirin-exacerbated respiratory disease and chronic rhinosinusitis patients. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 3(11), 866-876.
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Characterization of human upper airway epithelial progenitors.
Bravo, D. T., Soudry, E., Edward, J. A., Le, W., Nguyen, A. L., & Nayak, J. V. (2013). Characterization of human upper airway epithelial progenitors. International forum of allergy & rhinology, 3(10), 841-847.
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Characterization of human upper airway epithelial progenitors
Bravo, D. T., Soudry, E., Edward, J. A., Le, W., Nguyen, A. L., & Nayak, J. V. (2013). Characterization of human upper airway epithelial progenitors. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 3(10), 841-847.
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Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.
Cho, D.-Y., Nayak, J. V., Bravo, D. T., Le, W., Nguyen, A., & Fischer, H. (2013). Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis. International forum of allergy & rhinology, 3(5), 376-383.
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Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis
Cho, D.-Y., Nayak, J. V., Bravo, D. T., Le, W., Nguyen, A., & Fischer, H. (2013). Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 3(5), 376-383.
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Survival Outcomes in Acute Invasive Fungal Sinusitis: A Systematic Review and Quantitative Synthesis of Published Evidence
Turner, J. H., Soudry, E., Nayak, J. V., & Hwang, P. H. (2013). Survival Outcomes in Acute Invasive Fungal Sinusitis: A Systematic Review and Quantitative Synthesis of Published Evidence. LARYNGOSCOPE, 123(5), 1112-1118.
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Trends in incidence and susceptibility among methicillin-resistant Staphylococcus aureus isolated from intranasal cultures associated with rhinosinusitis.
Rujanavej, V., Soudry, E., Banaei, N., Baron, E. J., Hwang, P. H., & Nayak, J. V. (2013). Trends in incidence and susceptibility among methicillin-resistant Staphylococcus aureus isolated from intranasal cultures associated with rhinosinusitis. American journal of rhinology & allergy, 27(2), 134-137.
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Trends in incidence and susceptibility among methicillin-resistant Staphylococcus aureus isolated from intranasal cultures associated with rhinosinusitis
Rujanavej, V., Soudry, E., Banaei, N., Baron, E. J., Hwang, P. H., & Nayak, J. V. (2013). Trends in incidence and susceptibility among methicillin-resistant Staphylococcus aureus isolated from intranasal cultures associated with rhinosinusitis. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 27(2), 134-137.
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Low-frequency pulsed ultrasound in the nasal cavity and paranasal sinuses: a feasibility and distribution study
Patel, Z. M., Hwang, P. H., Chernomorsky, A., Bravo, D. T., Nguyen, B. L., & Nayak, J. V. (2012). Low-frequency pulsed ultrasound in the nasal cavity and paranasal sinuses: a feasibility and distribution study. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(4), 303-308.
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Nationwide incidence of major complications in endoscopic sinus surgery
Ramakrishnan, V. R., Kingdom, T. T., Nayak, J. V., Hwang, P. H., & Orlandi, R. R. (2012). Nationwide incidence of major complications in endoscopic sinus surgery. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(1), 34-39.
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Sinonasal seromucinous hamartomas: Clinical features and diagnostic dilemma
Figures, M. R., Nayak, J. V., Gable, C., & Chiu, A. G. (2010). Sinonasal seromucinous hamartomas: Clinical features and diagnostic dilemma. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 143(1), 165-166.
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Assessing the risk of irrigation bottle and fluid contamination after endoscopic sinus surgery
Lee, J. M., Nayak, J. V., Doghramji, L. L., Welch, K. C., & Chiu, A. G. (2010). Assessing the risk of irrigation bottle and fluid contamination after endoscopic sinus surgery. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 24(3), 197-199.
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Biofilms in chronic rhinosinusitis: A review
Cohen, M., Kofonow, J., Nayak, J. V., Palmer, J. N., Chiu, A. G., & Cohen, N. A. (2009). Biofilms in chronic rhinosinusitis: A review. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 23(3), 255-260.
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Head and neck epithelioid sarcoma in a child: Diagnostic dilemma and anterolateral thigh free flap reconstruction
Nayak, J. V., Teot, L. A., Vyas, Y., Snyderman, C. H., Toh, E. H., & Deleyiannis, F. Wb. (2008). Head and neck epithelioid sarcoma in a child: Diagnostic dilemma and anterolateral thigh free flap reconstruction. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 72(5), 719-724.
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Head and Neck Cancer Immunotherapy: Clinical Evaluation
Leibowitz, M. S., Nayak, J. V., & Ferris, R. L. (2008). Head and Neck Cancer Immunotherapy: Clinical Evaluation. CURRENT ONCOLOGY REPORTS, 10(2), 162-169.
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Deferring planned neck dissection following chemoradiation for stage IV head and neck cancer: The utility of PET-CT
Nayak, J. V., Walvekar, R. R., Andrade, R. S., Daamen, N., Lai, S. Y., & Branstetter, B. F. (2007). Deferring planned neck dissection following chemoradiation for stage IV head and neck cancer: The utility of PET-CT. LARYNGOSCOPE, 117(12), 2129-2134.
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Experience with the expanded endonasal approach for resection of the odontoid process in rheumatoid disease
Nayak, J. V., Gardner, P. A., Vescan, A. D., Carrau, R. L., Kassam, A. B., & Snyderman, C. H. (2007). Experience with the expanded endonasal approach for resection of the odontoid process in rheumatoid disease. AMERICAN JOURNAL OF RHINOLOGY, 21(5), 601-606.
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Phagocytosis induces lysosome remodeling and regulated presentation of particulate antigens by activated dendritic cells
Nayak, J. V., Hokey, D. A., Larregina, A., He, Y., Salter, R. D., & Falo, L. D. (2006). Phagocytosis induces lysosome remodeling and regulated presentation of particulate antigens by activated dendritic cells. JOURNAL OF IMMUNOLOGY, 177(12), 8493-8503.
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Role of antigen-processing machinery in the in vitro resistance of squamous cell carcinoma of the head and neck cells to recognition by CTL
Lopez-Albaitero, A., Nayak, J. V., Ogino, T., Machandia, A., Gooding, W., & Ferris, R. L. (2006). Role of antigen-processing machinery in the in vitro resistance of squamous cell carcinoma of the head and neck cells to recognition by CTL. JOURNAL OF IMMUNOLOGY, 176(6), 3402-3409.
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Current use of F-18-fluorodeoxyglucose positron emission tomography and combined positron emission tomography and computed tomography in squamous cell carcinoma of the head and neck
Zimmer, L. A., Branstetter, B. F., Nayak, J. V., & Johnson, J. T. (2005). Current use of F-18-fluorodeoxyglucose positron emission tomography and combined positron emission tomography and computed tomography in squamous cell carcinoma of the head and neck. LARYNGOSCOPE, 115(11), 2029-2034.
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Diagnostic utility of positron emission tomography-computed tomography for predicting malignancy in cystic neck masses in adults
Ferris, R. L., Branstetter, B. F., & Nayak, J. V. (2005). Diagnostic utility of positron emission tomography-computed tomography for predicting malignancy in cystic neck masses in adults. LARYNGOSCOPE, 115(11), 1979-1982.
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Sensitization with xenogeneic tissues alters the heavy chain repertoire of human anti-Ga1 alpha 1-3Ga1 antibodies
Yu, P. B., Parker, W., Nayak, J. V., & Platt, J. L. (2005). Sensitization with xenogeneic tissues alters the heavy chain repertoire of human anti-Ga1 alpha 1-3Ga1 antibodies. TRANSPLANTATION, 80(1), 102-109.
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Lipid-protamine-DNA-mediated antigen delivery to antigen-presenting cells results in enhanced anti-tumor immune responses
DiLeo, J., Banerjee, R., Whitmore, M., Nayak, J. V., Falo, L. D., & Huang, L. (2003). Lipid-protamine-DNA-mediated antigen delivery to antigen-presenting cells results in enhanced anti-tumor immune responses. MOLECULAR THERAPY, 7(5), 640-648.
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Myoepithelial neoplasia of the submandibular gland - Case report and therapeutic considerations
Nayak, J. V., Molina, J. T., Smith, J. C., Branstetter, B. F., Hunt, J. L., & Snyderman, C. H. (2003). Myoepithelial neoplasia of the submandibular gland - Case report and therapeutic considerations. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 129(3), 359-362.
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Primary lymphoma of the larynx: New diagnostic and therapeutic approaches
Nayak, J. V., Cook, J. R., Molina, J. T., Branch, M. P., Branstetter, B. F., & Myers, E. N. (2003). Primary lymphoma of the larynx: New diagnostic and therapeutic approaches. ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES, 65(6), 321-326.
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Intravenous injection of naked DNA encoding secreted flt3 ligand dramatically increases the number of dendritic cells and natural killer cells in vivo
He, Y. K., Pimenov, A. A., Nayak, J. V., Plowey, J., Falo, L. D., & Huang, L. (2000). Intravenous injection of naked DNA encoding secreted flt3 ligand dramatically increases the number of dendritic cells and natural killer cells in vivo. HUMAN GENE THERAPY, 11(4), 547-554.
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The dual phases of the response to neonatal exposure to a V-H family-restricted staphylococcal B cell superantigen
Silverman, G. J., Nayak, J. V., Warnatz, K., Hajjar, F. F., Cary, S., & Curtiss, V. E. (1998). The dual phases of the response to neonatal exposure to a V-H family-restricted staphylococcal B cell superantigen. JOURNAL OF IMMUNOLOGY, 161(10), 5720-5732.
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In vivo consequences of B cell superantigen immunization
Silverman, G. J., Nayak, J. V., Wagenknecht, R., & Warnatz, K. (1997). In vivo consequences of B cell superantigen immunization. B LYMPHOCYTES AND AUTOIMMUNITY, 815, 105-110.
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B-cell superantigens: molecular and cellular implications.
Silverman, G. J., Nayak, J. V., & La Cava, A. (1997). B-cell superantigens: molecular and cellular implications. International reviews of immunology, 14(4), 259-290.
Patient Comments
Patients comments are gathered from our Patient Satisfaction Survey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
SHC Patient, Aug 2015
Dr. Nayak is wonderful! I will definitely continue with him.
SHC Patient, Jul 2015
Dr. Nayak is an exceptional professional and I have been very comfortable with his abilities and decisions related my conditions.
SHC Patient, Jun 2015
Excellent treatment.
SHC Patient, Apr 2015
I went in with doubts but I'm happy I have Dr Nayak & Dr Teo.
SHC Patient, Apr 2015
Dr. Nayak has been so helpful and caring through all my visits and surgery! He carefully listens and addresses all concerns clearly. From the very beginning I had so much faith in Dr. Nayak. My day-to-day life has improved tremendously after surgery. I truly feel lucky that I was able to be treated by someone as knowledgeable and experienced as him. I am forever thankful Dr. Nayak and Stanford Hospital.
SHC Patient, Apr 2015
good
SHC Patient, Nov 2014
Best doctor patient outcome I've ever had.
SHC Patient, Nov 2014
Top ENT doc!
SHC Patient, Nov 2014
Dr. Nayak is the best! Has fixed problems and made health better.
SHC Patient, Oct 2014
Doctor was A-1 - caring, helpful, kind informative.
SHC Patient, Oct 2014
Dr. N____ was an expert in his field and provided a solution immediately. (NP) was well train and prepared.
SHC Patient, May 2014
Everyone very attentive, caring, and helpful.
SHC Patient, Mar 2014
Best ever!!!
SHC Patient, Jan 2014
AWESOME -
SHC Patient, Aug 2015
Dr. Nayak is wonderful! I will definitely continue with him.
SHC Patient, Jul 2015
Dr. Nayak is an exceptional professional and I have been very comfortable with his abilities and decisions related my conditions.
SHC Patient, Jun 2015
Excellent treatment.
SHC Patient, Apr 2015
I went in with doubts but I'm happy I have Dr Nayak & Dr Teo.
SHC Patient, Apr 2015
Dr. Nayak has been so helpful and caring through all my visits and surgery! He carefully listens and addresses all concerns clearly. From the very beginning I had so much faith in Dr. Nayak. My day-to-day life has improved tremendously after surgery. I truly feel lucky that I was able to be treated by someone as knowledgeable and experienced as him. I am forever thankful Dr. Nayak and Stanford Hospital.
SHC Patient, Apr 2015
good
SHC Patient, Nov 2014
Best doctor patient outcome I've ever had.
SHC Patient, Nov 2014
Top ENT doc!
SHC Patient, Nov 2014
Dr. Nayak is the best! Has fixed problems and made health better.
SHC Patient, Oct 2014
Doctor was A-1 - caring, helpful, kind informative.
SHC Patient, Oct 2014
Dr. N____ was an expert in his field and provided a solution immediately. (NP) was well train and prepared.
SHC Patient, May 2014
Everyone very attentive, caring, and helpful.
View All 14 Patient Comments »