Mark Nicolls

Publications

• Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension.
  Qian, J., Tian, W., Jiang, X., Tamosiuniene, R., Sung, Y. K., & Nicolls, M. R. (2015). Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension. Hypertension, 66(6), 1227-1239.
• Noninvasive monitoring of infection and rejection after lung transplantation.
  De Vlaminck, I., Martin, L., Kertesz, M., Patel, K., Kowarsky, M., & Quake, S. R. (2015). Noninvasive monitoring of infection and rejection after lung transplantation. Proceedings of the National Academy of Sciences of the United States of America, 112(43), 13336-13341.
• Cyclosporine Does Not Prevent Microvascular Loss in Transplantation but Can Synergize With a Neutrophil Elastase Inhibitor, Elafin, to Maintain Graft Perfusion During Acute Rejection
  Jiang, X., Nguyen, T. T., Tian, W., Sung, Y. K., Yuan, K., & Nicolls, M. R. (2015). Cyclosporine Does Not Prevent Microvascular Loss in Transplantation but Can Synergize With a Neutrophil Elastase Inhibitor, Elafin, to Maintain Graft Perfusion During Acute Rejection. AMERICAN JOURNAL OF TRANSPLANTATION, 15(7), 1768-1781.
• Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling Nickel, N. P., Spiekerkoetter, E., Gu, M., Li, C. G., Li, H., & Rabinovitch, M. (2015). Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 191(11), 1273-1286.
  
• Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension Rabinovitch, M., Guignabert, C., Humbert, M., & Nicolls, M. R. (2014). Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension. CIRCULATION RESEARCH, 115(1), 165-175.
  
• Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles Jiang, X., Malkovskiy, A. V., Tian, W., Sung, Y. K., Sun, W., & Nicolls, M. R. (2014). Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles. BIOMATERIALS, 35(2), 803-813.
  
• Temporal Response of the Human Virome to Immunosuppression and Antiviral Therapy De Vlaminck, I., Khush, K. K., Strehl, C., Kohli, B., Luikart, H., & Quake, S. R. (2013). Temporal Response of the Human Virome to Immunosuppression and Antiviral Therapy. CELL, 155(5), 1178-1187.
  
• Blocking Macrophage Leukotriene B-4 Prevents Endothelial Injury and Reverses Pulmonary Hypertension Tian, W., Jiang, X., Tamosiuniene, R., Sung, Y. K., Qian, J., & Nicolls, M. R. (2013). Blocking Macrophage Leukotriene B-4 Prevents Endothelial Injury and Reverses Pulmonary Hypertension. SCIENCE TRANSLATIONAL MEDICINE, 5(200).
  
• Targeting complement component 5a promotes vascular integrity and limits airway remodeling Khan, M. A., Maasch, C., Vater, A., Klussmann, S., Morser, J., & Nicolls, M. R. (2013). Targeting complement component 5a promotes vascular integrity and limits airway remodeling. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(15), 6061-6066.
  
• Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus. Jiang, X., Hsu, J. L., Tian, W., Yuan, K., Olcholski, M., & Nicolls, M. R. (2013). Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus. Journal of molecular medicine (Berlin, Germany).
  
• CD4(+) T Cells and Complement Independently Mediate Graft Ischemia in the Rejection of Mouse Orthotopic Tracheal Transplants Khan, M. A., Jiang, X., Dhillon, G., Beilke, J., Holers, V. M., & Nicolls, M. R. (2011). CD4(+) T Cells and Complement Independently Mediate Graft Ischemia in the Rejection of Mouse Orthotopic Tracheal Transplants. CIRCULATION RESEARCH, 109(11), 1290-U256.
  
• Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension Tamosiuniene, R., Tian, W., Dhillon, G., Wang, L., Sung, Y. K., & Nicolls, M. R. (2011). Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension. CIRCULATION RESEARCH, 109(8), 867-U120.
  
• Adenovirus-mediated HIF-1 alpha gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection Jiang, X., Khan, M. A., Tian, W., Beilke, J., Natarajan, R., & Nicolls, M. R. (2011). Adenovirus-mediated HIF-1 alpha gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection. JOURNAL OF CLINICAL INVESTIGATION, 121(6), 2336-2349.
  
• Lung Transplant Airway Hypoxia A Diathesis to Fibrosis? Dhillon, G. S., Zamora, M. R., Roos, J. E., Sheahan, D., Sista, R. R., & Nicolls, M. R. (2010). Lung Transplant Airway Hypoxia A Diathesis to Fibrosis?. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 182(2), 230-236.
  
• Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis Babu, A. N., Murakawa, T., Thurman, J. M., Miller, E. J., Henson, P. M., & Nicolls, M. R. (2007). Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis. JOURNAL OF CLINICAL INVESTIGATION, 117(12), 3774-3785.
  
• Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling. Nicolls MR*, Taraseviciene-Stewart L, Kraskauskas D, Scerbavicius R, Burns N, & Voelkel NF (*co-1st author). (2007). Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling. Am J Respir Crit Care Med, 175(12).
  
• Increased Resource Use in Lung Transplant Admissions in the Lung Allocation Score Era Maxwelll, B. G., Mooney, J. J., Lee, P. Hu., Levitt, J. E., Chhatwani, L., & Dhillon, G. S. (2015). Increased Resource Use in Lung Transplant Admissions in the Lung Allocation Score Era. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 191(3), 302-308.
  
• Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment during Pulmonary Angiogenesis Yuan, K., Orcholski, M. E., Panaroni, C., Shuffle, E. M., Huang, N. F., & Perez, V. A. J. (2015). Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment during Pulmonary Angiogenesis. AMERICAN JOURNAL OF PATHOLOGY, 185(1), 69-84.
  
• Unique Predictors of Mortality in Patients With Pulmonary Arterial Hypertension Associated With Systemic Sclerosis in the REVEAL Registry Chung, L., Farber, H. W., Benza, R., Miller, D. P., Parsons, L., & Zamanian, R. T. (2014). Unique Predictors of Mortality in Patients With Pulmonary Arterial Hypertension Associated With Systemic Sclerosis in the REVEAL Registry. CHEST, 146(6), 1494-1504.
  
• Impact of the lung allocation score on survival beyond 1 year. Maxwell, B. G., Levitt, J. E., Goldstein, B. A., Mooney, J. J., Nicolls, M. R., & Dhillon, G. S. (2014). Impact of the lung allocation score on survival beyond 1 year. American journal of transplantation , 14(10), 2288-2294.
  
• Impact of the Lung Allocation Score on Survival Beyond 1 Year Maxwell, B. G., Levitt, J. E., Goldstein, B. A., Mooney, J. J., Nicolls, M. R., & Dhillon, G. S. (2014). Impact of the Lung Allocation Score on Survival Beyond 1 Year. AMERICAN JOURNAL OF TRANSPLANTATION, 14(10), 2288-2294.
  
• Nuclear Factor kappa B Inhibition Reduces Lung Vascular Lumen Obliteration in Severe Pulmonary Hypertension in Rats Farkas, D., Alhussaini, A. A., Kraskauskas, D., Kraskauskiene, V., Cool, C. D., & Farkas, L. (2014). Nuclear Factor kappa B Inhibition Reduces Lung Vascular Lumen Obliteration in Severe Pulmonary Hypertension in Rats. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 51(3), 413-425.
  
• Graft microvascular disease in solid organ transplantation Jiang, X., Sung, Y. K., Tian, W., Qian, J., Semenza, G. L., & Nicolls, M. R. (2014). Graft microvascular disease in solid organ transplantation. JOURNAL OF MOLECULAR MEDICINE-JMM, 92(8), 797-810.
  
• Leukotrienes in pulmonary arterial hypertension Tian, W., Jiang, X., Sung, Y. K., Qian, J., Yuan, K., & Nicolls, M. R. (2014). Leukotrienes in pulmonary arterial hypertension. IMMUNOLOGIC RESEARCH, 58(2-3), 387-393.
  
• Complement components as potential therapeutic targets for asthma treatment Khan, M. A., Nicolls, M. R., Surguladze, B., & Saadoun, I. (2014). Complement components as potential therapeutic targets for asthma treatment. RESPIRATORY MEDICINE, 108(4), 543-549.
  
• Efficacy of Transthoracic Echocardiography for Diagnosing Heart Failure in Septic Shock Beraud, A.-S., Guillamet, C. V., Hammes, J. L., Meng, L., Nicolls, M. R., & Hsu, J. L. (2014). Efficacy of Transthoracic Echocardiography for Diagnosing Heart Failure in Septic Shock. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 347(4), 295-298.
  
• Application of a non-amplification-based technology to detect invasive fungal pathogens Hsu, J. L., Binkley, J., Clemons, K. V., Stevens, D. A., Nicolls, M. R., & Holodniy, M. (2014). Application of a non-amplification-based technology to detect invasive fungal pathogens. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 78(2), 137-140.
  
• Working toward immune tolerance in lung transplantation. Jiang, X., & Nicolls, M. R. (2014). Working toward immune tolerance in lung transplantation. The Journal of clinical investigation, 1-4.
  
• Traumatic Brain Injury: Lungs in a RAGE. Nicolls, M. R., & Laubach, V. E. (2014). Traumatic Brain Injury: Lungs in a RAGE. Science translational medicine, 6(252), 252fs34.
  
• Macrophages in solid organ transplantation. Jiang, X., Tian, W., Sung, Y. K., Qian, J., & Nicolls, M. R. (2014). Macrophages in solid organ transplantation. Vascular cell, 6(1), 5-?.
  
• The Critical Role of mRNA Destabilizing Protein Heterogeneous Nuclear Ribonucleoprotein D in 3 ' Untranslated Region-Mediated Decay of Low-Density Lipoprotein Receptor mRNA in Liver Tissue Singh, A. B., Li, H., Kan, C. F. K., Dong, B., Nicolls, M. R., & Liu, J. (2014). The Critical Role of mRNA Destabilizing Protein Heterogeneous Nuclear Ribonucleoprotein D in 3 ' Untranslated Region-Mediated Decay of Low-Density Lipoprotein Receptor mRNA in Liver Tissue. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 34(1), 8-?.
  
• Aspergillus fumigatus Invasion Increases with Progressive Airway Ischemia Hsu, J. L., Khan, M. A., Sobel, R. A., Jiang, X., Clemons, K. V., & Nicolls, M. R. (2013). Aspergillus fumigatus Invasion Increases with Progressive Airway Ischemia. PLOS ONE, 8(10).
  
• Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus Jiang, X., Hsu, J. L., Tian, W., Yuan, K., Olcholski, M., & Nicolls, M. R. (2013). Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus. JOURNAL OF MOLECULAR MEDICINE-JMM, 91(9), 1081-1093.
  
• Epithelial to mesenchymal transition in murine tracheal allotransplantation: an immunohistochemical observation. Konoeda, C., Koinuma, D., Morishita, Y., Sano, A., Nagayama, K., & Murakawa, T. (2013). Epithelial to mesenchymal transition in murine tracheal allotransplantation: an immunohistochemical observation. Transplantation proceedings, 45(5), 1797-1801.
  
• Editorial: Developing Better Biomarkers for Connective Tissue DiseaseAssociated Interstitial Lung Disease: Citrullinated Hsp90 Autoantibodies in Rheumatoid Arthritis Deane, K. D., & Nicolls, M. R. (2013). Editorial: Developing Better Biomarkers for Connective Tissue DiseaseAssociated Interstitial Lung Disease: Citrullinated Hsp90 Autoantibodies in Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 65(4), 864-868.
  
• Complement-mediated microvascular injury leads to chronic rejection. Khan, M. A., & Nicolls, M. R. (2013). Complement-mediated microvascular injury leads to chronic rejection. Advances in experimental medicine and biology, 735, 233-246.
  
• Pathobiology of pulmonary arterial hypertension and right ventricular failure Voelkel, N. F., Gomez-Arroyo, J., Abbate, A., Bogaard, H. J., & Nicolls, M. R. (2012). Pathobiology of pulmonary arterial hypertension and right ventricular failure. EUROPEAN RESPIRATORY JOURNAL, 40(6), 1555-1565.
  
• Severe Pulmonary Arterial Hypertension Induced by SU5416 and Ovalbumin Immunization Mizuno, S., Farkas, L., Al Husseini, A., Farkas, D., Gomez-Arroyo, J., & Voelkel, N. F. (2012). Severe Pulmonary Arterial Hypertension Induced by SU5416 and Ovalbumin Immunization. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 47(5), 679-687.
  
• New methods for monitoring dynamic airway tissue oxygenation and perfusion in experimental and clinical transplantation Khan, M. A., Dhillon, G., Jiang, X., Lin, Y.-C., & Nicolls, M. R. (2012). New methods for monitoring dynamic airway tissue oxygenation and perfusion in experimental and clinical transplantation. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 303(10), L861-L869.
  
• New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis. Nicolls, M. R., Mizuno, S., Taraseviciene-Stewart, L., Farkas, L., Drake, J. I., & Bogaard, H. J. (2012). New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis. Pulmonary circulation, 2(4), 434-442.
  
• Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth. Hilgendorff, A., Parai, K., Ertsey, R., Juliana Rey-Parra, G., Thébaud, B., & Bland, R. D. (2012). Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth. American journal of physiology. Lung cellular and molecular physiology, 303(3), L215-27.
  
• Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth Hilgendorff, A., Parai, K., Ertsey, R., Rey-Parra, G. J., Thebaud, B., & Bland, R. D. (2012). Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 303(3), L215-L227.
  
• A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects Gomez-Arroyo, J., Saleem, S. J., Mizuno, S., Syed, A. A., Bogaard, H. J., & Voelkel, N. F. (2012). A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 302(10), L977-L991.
  
• Potential for overuse of corticosteroids and vasopressin in septic shock. Hsu, J. L., Liu, V., Patterson, A. J., Martin, G. S., Nicolls, M. R., & Russell, J. A. (2012). Potential for overuse of corticosteroids and vasopressin in septic shock. Critical care (London, England), 16(5), 447.
  
• Potential for overuse of corticosteroids and vasopressin in septic shock Hsu, J. L., Liu, V., Patterson, A. J., Martin, G. S., Nicolls, M. R., & Russell, J. A. (2012). Potential for overuse of corticosteroids and vasopressin in septic shock. CRITICAL CARE, 16(5).
  
• Inhibiting Lung Elastase Activity Enables Lung Growth in Mechanically Ventilated Newborn Mice Hilgendorff, A., Parai, K., Ertsey, R., Jain, N., Navarro, E. F., & Bland, R. D. (2011). Inhibiting Lung Elastase Activity Enables Lung Growth in Mechanically Ventilated Newborn Mice. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 184(5), 537-546.
  
• Regulatory T Cells and Pulmonary Hypertension Tamosiuniene, R., & Nicolls, M. R. (2011). Regulatory T Cells and Pulmonary Hypertension. TRENDS IN CARDIOVASCULAR MEDICINE, 21(6), 166-171.
  
• Survival in Pulmonary Hypertension Registries The Importance of Incident Cases Response Chung, L., Liu, J., Parsons, L. S., Hassoun, P. M., McGoon, M. D., & Zamanian, R. T. (2011). Survival in Pulmonary Hypertension Registries The Importance of Incident Cases Response. CHEST, 139(6), 1548-1549.
  
• The Role of C3 Activation in Airway Hypoxia and Ischemia in Murine Model of Orthotopic Tracheal Transplantation Khan, M. A., Jiang, X., Atkinson, C., Tomlinson, S., & Nicolls, M. R. (2011). The Role of C3 Activation in Airway Hypoxia and Ischemia in Murine Model of Orthotopic Tracheal Transplantation. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 30(4), S130-S131.
  
• Immunomodulatory strategies prevent the development of autoimmune emphysema Hanaoka, M., Nicolls, M. R., Fontenot, A. P., Kraskauskas, D., Mack, D. G., & Taraseviciene-Stewart, L. (2010). Immunomodulatory strategies prevent the development of autoimmune emphysema. RESPIRATORY RESEARCH, 11.
  
• Strategic Plan for Lung Vascular Research An NHLBI-ORDR Workshop Report Erzurum, S., Rounds, S. I., Stevens, T., Aldred, M., Aliotta, J., & Moore, T. M. (2010). Strategic Plan for Lung Vascular Research An NHLBI-ORDR Workshop Report. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 182(12), 1554-1562.
  
• Characterization of Connective Tissue Disease-Associated Pulmonary Arterial Hypertension From REVEAL Identifying Systemic Sclerosis as a Unique Phenotype Chung, L., Liu, J., Parsons, L., Hassoun, P. M., McGoon, M., & Zamanian, R. T. (2010). Characterization of Connective Tissue Disease-Associated Pulmonary Arterial Hypertension From REVEAL Identifying Systemic Sclerosis as a Unique Phenotype. CHEST, 138(6), 1383-1394.
  
• Bronchial blood supply after lung transplantation without bronchial artery revascularization Nicolls, M. R., & Zamora, M. R. (2010). Bronchial blood supply after lung transplantation without bronchial artery revascularization. CURRENT OPINION IN ORGAN TRANSPLANTATION, 15(5), 563-567.
  
• Immune Reconstitution Prevents Autoimmune Inflammation and Right Ventricular Remodeling in Immunodeficiency-Associated Pulmonary Hypertension Tamosiuniene, R., Long, C., Ambler, K., Sung, Y., Gera, L., & Nicolls, M. (2009). Immune Reconstitution Prevents Autoimmune Inflammation and Right Ventricular Remodeling in Immunodeficiency-Associated Pulmonary Hypertension. CIRCULATION, 120(18), S1135-S1135.
  
• Prevention of Adverse Right Ventricular Remodeling and Autoimmune Inflammation after Splenocyte Therapy in Pulmonary Hypertension: Contribution of HOX11+, C-kit+, FOXP3+Cells Tamosiuniene, R., Long, C., Ambler, K., Wang, L., Gera, L., & Nicolls, M. (2009). Prevention of Adverse Right Ventricular Remodeling and Autoimmune Inflammation after Splenocyte Therapy in Pulmonary Hypertension: Contribution of HOX11+, C-kit+, FOXP3+Cells. CLINICAL IMMUNOLOGY, 131, S69-S70.
  
• Increased regulatory and decreased CD8+ cytotoxic T cells in the blood of patients with idiopathic pulmonary arterial hypertension Ulrich, S., Nicolls, M. R., Taraseviciene, L., Speich, R., & Voelkel, N. (2008). Increased regulatory and decreased CD8+ cytotoxic T cells in the blood of patients with idiopathic pulmonary arterial hypertension. RESPIRATION, 75(3), 272-280.
  
• Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin El Mezayen, R., El Gazzar, M., Seeds, M. C., McCall, C. E., Dreskin, S. C., & Nicolls, M. R. (2007). Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin. IMMUNOLOGY LETTERS, 111(1), 36-44.
  
• Oxidant stress, immune dysregulation, and vascular function in type I diabetes Nicolls, M. R., Haskins, K., & Flores, S. C. (2007). Oxidant stress, immune dysregulation, and vascular function in type I diabetes. ANTIOXIDANTS & REDOX SIGNALING, 9(7), 879-889.
  
• Hypoxia and the lung: Beyond hypoxic vasoconstriction Nicolls, M. R., & Voelkel, N. F. (2007). Hypoxia and the lung: Beyond hypoxic vasoconstriction. ANTIOXIDANTS & REDOX SIGNALING, 9(6), 741-743.
  
• Transfer of allograft specific tolerance requires CD4(+)CD25(+)T cells but not interleukin-4 or transforming growth factor-beta and cannot induce tolerance to linked antigens Hall, B. M., Plain, K. M., Verma, N. D., Tran, G. T., Boyd, R., & Hodgkinson, S. J. (2007). Transfer of allograft specific tolerance requires CD4(+)CD25(+)T cells but not interleukin-4 or transforming growth factor-beta and cannot induce tolerance to linked antigens. TRANSPLANTATION, 83(8), 1075-1084.
  
• Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation El Gazzar, M. A., El Mezayen, R., Nicolls, M. R., & Dreskin, S. C. (2007). Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1770(4), 556-564.
  
• The matrix comes to lung transplantation Babu, A. N., & Nicolls, M. R. (2007). The matrix comes to lung transplantation. TRANSPLANTATION, 83(6), 683-684.
  
• Angiogenesis in chronic lung disease Voelkel, N. F., Douglas, I. S., & Nicolls, M. (2007). Angiogenesis in chronic lung disease. CHEST, 131(3), 874-879.
  
• Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease? Taraseviciene-Stewart, L., Douglas, I. S., Nana-Sinkam, P. S., Lee, J. D., Tuder, R. M., & Voelkel, N. F. (2006). Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease?. Proceedings of the American Thoracic Society, 3(8), 687-690.
  
• Critical pathways leading to obliterative bronchiolitis in lung allografts Babu, A. N., & Nicolls, M. R. (2006). Critical pathways leading to obliterative bronchiolitis in lung allografts. CURRENT OPINION IN ORGAN TRANSPLANTATION, 11(5), 483-489.
  
• Mechanisms of autoimmune emphysema. Taraseviciene-Stewart, L., Burns, N., Kraskauskas, D., Nicolls, M. R., Tuder, R. M., & Voelkel, N. F. (2006). Mechanisms of autoimmune emphysema. Proceedings of the American Thoracic Society, 3(6), 486-487.
  
• Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation El Mezayen, R., El Gazzar, M., Nicolls, M. R., Marecki, J. C., Dreskin, S. C., & Nomiyama, H. (2006). Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation. IMMUNOLOGY LETTERS, 106(1), 72-81.
  
• Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma El Gazzar, M., El Mezayen, R., Nicolls, M. R., Marecki, J. C., & Dreskin, S. C. (2006). Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1760(7), 1088-1095.
  
• Anti-inflammatory effect of thymoquinone in a mouse model of allergic lung inflammation El Gazzar, M., El Mezayen, R., Marecki, J. C., Nicolls, M. R., Canastar, A., & Dreskin, S. C. (2006). Anti-inflammatory effect of thymoquinone in a mouse model of allergic lung inflammation. INTERNATIONAL IMMUNOPHARMACOLOGY, 6(7), 1135-1142.
  
• LFA-1 (CD11a) as a therapeutic target Nicolls, M. R., & Gill, R. G. (2006). LFA-1 (CD11a) as a therapeutic target. AMERICAN JOURNAL OF TRANSPLANTATION, 6(1), 27-36.
  
• Autoimmunity and pulmonary hypertension: a perspective Nicolls, M. R., Taraseviciene-Stewart, L., Rai, P. R., Badesch, D. B., & Voelkel, N. F. (2005). Autoimmunity and pulmonary hypertension: a perspective. EUROPEAN RESPIRATORY JOURNAL, 26(6), 1110-1118.
  
• The protective role of T-lymphocytes in pulmonary vascular remodeling Taraseviciene-Stewart, L., Kraskauskas, D., Scerbavicins, R., Burns, N., Cool, C. D., & Voelkel, N. F. (2005). The protective role of T-lymphocytes in pulmonary vascular remodeling. CHEST, 128(6), 571S-572S.
  
• Type 2 diabetes mellitus as a conformational disease. Hayden, M. R., Tyagi, S. C., Kerklo, M. M., & Nicolls, M. R. (2005). Type 2 diabetes mellitus as a conformational disease. JOP : Journal of the pancreas, 6(4), 287-302.
  
• Chemokine-mediated angiogenesis: an essential link in the evolution of airway fibroses? Douglas, I. S., & Nicolls, T. R. (2005). Chemokine-mediated angiogenesis: an essential link in the evolution of airway fibroses?. JOURNAL OF CLINICAL INVESTIGATION, 115(5), 1133-1136.
  
• Simultaneous LFA-1 and CD40 ligand antagonism prevents airway remodeling in orthotopic airway transplantation: Implications for the role of respiratory epithelium as a modulator of fibrosis Murakawa, T., Kerklo, M. M., Zamora, M. R., Wei, Y., Gill, R. G., & Nicolls, M. R. (2005). Simultaneous LFA-1 and CD40 ligand antagonism prevents airway remodeling in orthotopic airway transplantation: Implications for the role of respiratory epithelium as a modulator of fibrosis. JOURNAL OF IMMUNOLOGY, 174(7), 3869-3879.
  
• An animal model of autoimmune emphysema Taraseviciene-Stewart, L., Scerbavicius, R., Chloe, K. H., Moore, M., Sullivan, A., & Voelkel, N. F. (2005). An animal model of autoimmune emphysema. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 171(7), 734-742.
  
• Following universal prophylaxis with intravenous ganciclovir and cytomegalovirus immune globulin, valganciclovir is safe and effective for prevention of CMV infection following lung transplantation Zamora, M. R., Nicolls, M. R., Hodges, T. N., Marquesen, J., Astor, T., & Weill, D. (2004). Following universal prophylaxis with intravenous ganciclovir and cytomegalovirus immune globulin, valganciclovir is safe and effective for prevention of CMV infection following lung transplantation. AMERICAN JOURNAL OF TRANSPLANTATION, 4(10), 1635-1642.
  
• The Clinical and Biological Relationship between Type II Diabetes Mellitus and Alzheimer's Disease Nicolls, M. R. (2004). The Clinical and Biological Relationship between Type II Diabetes Mellitus and Alzheimer's Disease. CURRENT ALZHEIMER RESEARCH, 1(1), 47-54.
  
• Gene microarray study corroborates proteomic findings in rodent islet cells Cardozo, A. K., Berthou, L., Kruhoffer, M., Orntoft, T., Nicolls, M. R., & Eizirik, D. L. (2003). Gene microarray study corroborates proteomic findings in rodent islet cells. JOURNAL OF PROTEOME RESEARCH, 2(5), 553-555.
  
• Proteomics as a tool for discovery: Proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets Nicolls, M. R., D'Antonio, J. M., Hutton, J. C., Gill, R. G., Czwornog, J. L., & Duncan, M. W. (2003). Proteomics as a tool for discovery: Proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets. JOURNAL OF PROTEOME RESEARCH, 2(2), 199-205.
  
• CD4-dependent generation of dominant transplantation tolerance induced by simultaneous perturbation of CD154 and LFA-1 pathways Nicolls, M. R., Coulombe, M., Beilke, J., Gelhuas, H. C., & Gill, R. G. (2002). CD4-dependent generation of dominant transplantation tolerance induced by simultaneous perturbation of CD154 and LFA-1 pathways. JOURNAL OF IMMUNOLOGY, 169(9), 4831-4839.
  
• Interferon-gamma is not a universal requirement for islet allograft survival Nicolls, M. R., Coulombe, M., Diamond, A. S., Beilke, J., & Gill, R. G. (2002). Interferon-gamma is not a universal requirement for islet allograft survival. TRANSPLANTATION, 74(4), 472-477.
  
• Reversal of experimental allergic encephalomyelitis with non-mitogenic, non-depleting anti-CD3 mAb therapy with a preferential effect on T(h)1 cells that is augmented by IL-4 Tran, G. T., CARTER, N., He, X. Y., Spicer, T. S., Plain, K. M., & Hodgkinson, S. J. (2001). Reversal of experimental allergic encephalomyelitis with non-mitogenic, non-depleting anti-CD3 mAb therapy with a preferential effect on T(h)1 cells that is augmented by IL-4. INTERNATIONAL IMMUNOLOGY, 13(9), 1109-1120.
  
• The basis of immunogenicity of endocrine allografts Nicolls, M. R., Coulombe, M., & Gill, R. G. (2001). The basis of immunogenicity of endocrine allografts. CRITICAL REVIEWS IN IMMUNOLOGY, 21(1-3), 87-101.
  
• Anti-LFA-1 therapy induces long-term islet allograft acceptance in the absence of IFN-gamma or IL-4 Nicolls, M. R., Coulombe, M., Yang, H., Bolwerk, A., & Gill, R. G. (2000). Anti-LFA-1 therapy induces long-term islet allograft acceptance in the absence of IFN-gamma or IL-4. JOURNAL OF IMMUNOLOGY, 164(7), 3627-3634.
  
• Diffuse alveolar hemorrhage with underlying pulmonary capillaritis in the retinoic acid syndrome Nicolls, M. R., Terada, L. S., Tuder, R. M., Prindiville, S. A., & Schwarz, M. I. (1998). Diffuse alveolar hemorrhage with underlying pulmonary capillaritis in the retinoic acid syndrome. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 158(4), 1302-1305.
  
• Recognition and treatment of diffuse panbronchiolitis Nicolls, M. R., Weiss, S. M., & Schwarz, M. I. (1998). Recognition and treatment of diffuse panbronchiolitis. INFECTIONS IN MEDICINE, 15(9), 657-662.
  
• INDUCTION OF TOLERANCE TO HEART ALLOGRAFTS IN RATS USING POSTTRANSPLANT TOTAL LYMPHOID IRRADIATION AND ANTI-T CELL ANTIBODIES WOODLEY, S. L., Gurley, K. E., HOFFMANN, S. L., Nicolls, M. R., Hagberg, R., & Strober, S. (1993). INDUCTION OF TOLERANCE TO HEART ALLOGRAFTS IN RATS USING POSTTRANSPLANT TOTAL LYMPHOID IRRADIATION AND ANTI-T CELL ANTIBODIES. TRANSPLANTATION, 56(6), 1443-1447.
  
• INDUCTION OF LONG-TERM SPECIFIC TOLERANCE TO ALLOGRAFTS IN RATS BY THERAPY WITH AN ANTI-CD3-LIKE MONOCLONAL-ANTIBODY Nicolls, M. R., AVERSA, G. G., Pearce, N. W., Spinelli, A., Berger, M. F., & Hall, B. M. (1993). INDUCTION OF LONG-TERM SPECIFIC TOLERANCE TO ALLOGRAFTS IN RATS BY THERAPY WITH AN ANTI-CD3-LIKE MONOCLONAL-ANTIBODY. TRANSPLANTATION, 55(3), 459-468.