Department of Applied Physics

Description

Biophysics

Mark Schnitzer is an Associate Professor with a joint appointment in the Departments of Applied Physics and Biology and is an Investigator of the Howard Hughes Medical Institute. He is a faculty member of the Neuroscience, Biophysics, and Molecular Imaging Programs in the Stanford School of Medicine, as well as of the Stanford Neuroscience Institute. Dr. Schnitzer has longstanding interests in neural circuit dynamics and optical imaging, and his laboratory has three major research efforts: • Development and application of fiber-optic, micro-optic, and nanophotonic imaging techniques for studies of learning and memory in behaving mice and for clinical uses in humans. • In vivo fluorescence imaging and behavioral studies of hippocampal-dependent cognition and learning • Development of high-throughput, massively parallel imaging techniques for studying brain function in large numbers of Drosophila concurrently.

Courses Taught

• Neuronal Biophysics
• Photons, Biological Photosynthesis, and Quantum Mechanics
• Advanced Imaging Lab in Biophysics

Selected Publications

• In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope
• Fiber-optic fluorescence imaging
• In vivo imaging of mammalian cochlear blood flow using fluorescence microendoscopy
• Fast-scanning two-photon fluorescence imaging based on a microelectromechanical systems two-dimensional scanning mirror
• Minimally invasive high-speed imaging of sarcomere contractile dynamics in mice and humans
• High-speed, miniaturized fluorescence microscopy in freely moving mice
• Motor behavior activates Bergmann glial networks
• In vivo fluorescence imaging with high-resolution microlenses
• Advances in light microscopy for neuroscience
• In vivo brain imaging using a portable 2.9 g two-photon microscope based on a microelectromechanical systems scanning mirror
• Automated analysis of cellular signals from large-scale calcium imaging data