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| Genomic Services |
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| Protein Services |
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| Oligo Synthesis (back to top) |
- In silico investigation of FOXM1 binding and novel inhibitors in epithelial ovarian cancer.
Yi Chen, Eliza A. Ruben, Jayakumar Rajadas, Nelson N.H. Teng.
Bioorg Med Chem., (2015), 23(15):4576-82.
- Complete biosynthesis of opioids in yeast.
Stephanie Galanie, Kate Thodey, Isis J. Trenchard, Maria Filsinger Interrante, Christina D. Smolke.
Science, (2015), aac9373.
- Organocatalytic removal of formaldehyde adducts from RNA and DNA bases.
Saswata Karmakar, Emily M. Harcourt, David S. Hewings, Alexander F. Lovejoy, David M. Kurtz, Thomas Ehrenschwender, Luzi J. Barandun, Caroline Roost, Ash A. Alizadeh & Eric T. Kool.
Nature Chemistry, (2015), 7:752–758.
- Capture, unfolding, and detection of individual tRNA molecules using a nanopore device.
Smith Andrew M, AbuShumays Robin L, Akeson Mark, Bernick David L.
Frontiers in Bioengineering and Biotechnology, (2015), 3:91.
- Engineering strategies for the fermentative production of plant alkaloids in yeast.
Isis J. Trenchard, Christina D. Smolke.
Metabolic Engineering, (2015), 30:96-104.
- Formulation of Anti-miR-21 and 4‑Hydroxytamoxifen Co-loaded Biodegradable Polymer Nanoparticles and Their Antiproliferative Effect on Breast Cancer Cells.
Rammohan Devulapally, Thillai V. Sekar, and Ramasamy Paulmurugan.
Mol. Pharmaceutics, (2015).
- Synthetic feedback control using an RNAi-based gene-regulatory device.
Ryan J Bloom, Sally M Winkler and Christina D Smolke.
Journal of Biological Engineering, (2015), 9:5.
- Elafin Reverses Pulmonary Hypertension via Caveolin-1 Dependent Bone Morphogenetic Protein Signaling.
Nickel NP, Spiekerkoetter E, Gu M, Li CG, Li H, Kaschwich M, Diebold I, Hennigs JK, Kim KY, Miyagawa K, Wang L, Cao A, Sa S, Jiang X, Stockstill RW, Nicolls MR, Zamanian RT, Bland RD, Rabinovitch M.
Am J Respir Crit Care Med., (2015).
- Systematic Discovery of Xist RNA Binding Proteins.
Chu C, Zhang QC, da Rocha ST, Flynn RA, Bharadwaj M, Calabrese JM, Magnuson T, Heard E, Chang HY.
Cell, (2015), pii:S0092-8674(15)00312-8.
- A system for multilocus chromosomal integration and transformation-free selection marker rescue.
Michael S. Siddiqui, Atri Choksi and Christina D. Smolke.
FEMS Yeast Research, (2014), 14(8):1171–1185.
- Kinetic Mechanism at the Branchpoint between the DNA Synthesis and Editing Pathways in Individual DNA Polymerase Complexes.
Kate R. Lieberman, Joseph M. Dahl, and Hongyun Wang.
J. Am. Chem. Soc., (2014), 136(19):7117–7131.
- Coupling isotachophoresis with affinity chromatography for rapid and selective purification with high column utilization, part 2: experimental study.
Shkolnikov V, Santiago JG.
Anal Chem., (2014), 86(13):6229-36.
- Precise gene deletion and replacement using the CRISPR/Cas9 system in human cells.
Zheng Q, Cai X, Tan MH, Schaffert S, Arnold CP, Gong X, Chen CZ, Huang S.
Biotechniques, (2014), 57(3):115-24.
- Protein-responsive ribozyme switches in eukaryotic cells.
Andrew B. Kennedy, James V. Vowles, Leo d'Espaux, and Christina D. Smolke.
Nucl. Acids Res., (2014).
- A quantitative framework for the forward design of synthetic miRNA circuits.
Ryan J Bloom, Sally M Winkler & Christina D Smolke.
Nature Methods, (2014), 1548-7105.
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Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus.
He Zhang, Michael J. Zeitz, Hong Wang, Beibei Niu, Shengfang Ge, Wei Li, Jiuwei Cui, Guanjun Wang, Guanxiang Qian, Michael J. Higgins, Xianqun Fan, Andrew R. Hoffman, Ji-Fan Hu.
J. Cell Biol, (2014), 204:61-75.
- Hard X-ray-induced optical luminescence via biomolecule-directed metal clusters.
Osakada Y, Pratx G, Sun C, Sakamoto M, Ahmad M, Volotskova O, Ong Q, Teranishi T, Harada Y, Xing L, Cui B.
Chem Commun (Camb), (2014), 50(27):3549-51.
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Dynamics of Translocation and Substrate Binding in Individual Complexes Formed with Active Site Mutants of Φ29 DNA Polymerase.
Dahl JM, Wang H, Lazaro JM, Salas M, Lieberman KR.
J Biol Chem. (2014).
- Microdroplet temperature calibration via thermal dissociation of quenched DNA oligomers.
Eric W. Hall and Gregory W. Faris.
Biomed. Opt. Express, (2014), 5:737-751.
- Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes.
Jason D Buenrostro, Carlos L Araya, Lauren M Chircus, Curtis J Layton, Howard Y Chang, Michael P Snyder & William J Greenleaf.
Nature Biotechnology, (2014).
- Error rates for nanopore discrimination among cytosine, methylcytosine, and hydroxymethylcytosine along individual DNA strands.
Schreiber J, Zachary L. Wescoe ZL, Abu-Shumays R, Vivian JT, Baatar B, Karplus K, Akeson M.
Proc Natl Acad Sci USA, (2013), 110(47):18910-18915.
- Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase.
Manrao EA, Derrington IM, Laszlo AH, Langford KW, Hopper MK, Gillgren N, Pavlenok M, Niederweis M, Gundlach JH.
Nature Biotechnology, (2012), 30:349-353.
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| Gene Expression/Bioanalyzer QC (back to top) |
- Comprehensive genomic profiles of small cell lung cancer.
George J, Lim JS, Jang SJ, Cun Y, Ozretić L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco G, Müller C, Dahmen I, Jahchan NS, Park KS, Yang D, Karnezis AN, Vaka D, Torres A, Wang MS, Korbel JO, Menon R, Chun SM, Kim D, Wilkerson M, Hayes N, Engelmann D, Pützer B, Bos M, Michels S, Vlasic I, Seidel D, Pinther B, Schaub P, Becker C, Altmüller J, Yokota J, Kohno T, Iwakawa R, Tsuta K, Noguchi M, Muley T, Hoffmann H, Schnabel PA, Petersen I, Chen Y, Soltermann A, Tischler V, Choi CM, Kim YH, Massion PP, Zou Y, Jovanovic D, Kontic M, Wright GM, Russell PA, Solomon B, Koch I, Lindner M, Muscarella LA, la Torre A, Field JK, Jakopovic M, Knezevic J, Castaños-Vélez E, Roz L, Pastorino U, Brustugun OT, Lund-Iversen M, Thunnissen E, Köhler J, Schuler M, Botling J, Sandelin M, Sanchez-Cespedes M, Salvesen HB, Achter V, Lang U, Bogus M, Schneider PM, Zander T, Ansén S, Hallek M, Wolf J, Vingron M, Yatabe Y, Travis WD, Nürnberg P, Reinhardt C, Perner S, Heukamp L, Büttner R, Haas SA, Brambilla E, Peifer M, Sage J, Thomas RK.
Nature, (2015), 524(7563):47-53.
- Generation and transcriptional programming of intestinal dendritic cells: essential role of retinoic acid.
R Zeng, M Bscheider, K Lahl, M Lee, and E C Butcher.
Mucosal Immunology, (2015).
- Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes.
Taylor SE, Henry Li Y, Wong WH, Bhutani N.
Arthritis Rheumatol, (2015).
- Early induction of a prechondrogenic population allows efficient generation of stable chondrocytes from human induced pluripotent stem cells.
Lee J, Taylor SE, Smeriglio P, Lai J, Maloney WJ, Yang F, Bhutani N.
FASEB J., (2015).
- A Continuous Molecular Roadmap to iPSC Reprogramming through Progression Analysis of Single-Cell Mass Cytometry.
Eli R. Zunder, Ernesto Lujan, Yury Goltsev, Marius Wernig, Garry P. Nolan.
Cell Stem Cell, (2015), 16(3):323-337.
- Tenofovir Disoproxil Fumarate: Toxicity, Toxicokinetics, and Toxicogenomics Analysis After 13 Weeks of Oral Administration in Mice.
Hanna H. Ng, Howard Stock, L. J Rausch, Deborah I. Bunin, Abraham Wang, Shirley Brill, Jason Gow and Jon C. Mirsalis.
Int J Toxicol., (2015), pii: 1091581814565669.
- Identification and Specification of the Mouse Skeletal Stem Cell.
Charles K.F. Chan, Eun Young Seo, James Y. Chen, David Lo, Adrian McArdle, Rahul Sinha, Ruth Tevlin, Jun Seita, Justin Vincent-Tompkins, Taylor Wearda, Wan-Jin Lu, Kshemendra Senarath-Yapa, Michael T. Chung, Owen Marecic, Misha Tran, Kelley S. Yan, Rosalynd Upton, Graham G. Walmsley, Andrew S. Lee, Debashis Sahoo, Calvin J. Kuo, Irving L. Weissman, Michael T. Longaker.
Cell, (2015), 160(1-2):285-298.
- Transcriptional programs of lymphoid tissue capillary and high endothelium reveal control mechanisms for lymphocyte homing.
Mike Lee, Helena Kiefel, Melissa D LaJevic, Matthew S Macauley, Hiroto Kawashima, Edward O'Hara, Junliang Pan, James C Paulson & Eugene C Butcher.
Nature Immunology, (2014), 15:982–995.
- Global Transcriptional Profiling Reveals Distinct Functions of Thymic Stromal Subsets and Age-Related Changes during Thymic Involution.
Sanghee Ki, Daechan Park, Hilary J. Selden, Jun Seita, Haewon Chung, Jonghwan Kim, Vishwanath R. Iyer, Lauren I.R. Ehrlich.
Cell Reports, (2014), 9(1):402-415.
- Prostaglandin signaling suppresses beneficial microglial function in Alzheimer’s disease models.
Jenny U. Johansson, Nathaniel S. Woodling, Qian Wang, Maharshi Panchal, Xibin Liang, Angel Trueba-Saiz, Holden D. Brown, Siddhita D. Mhatre, Taylor Loui, and Katrin I. Andreasson.
J Clin Invest., (2014).
- Upregulation of CD11A on Hematopoietic Stem Cells Denotes the Loss of Long-Term Reconstitution Potential.
John W. Fathman, Nathaniel B. Fernhoff, Jun Seita, Connie Chao, Vanessa M. Scarfone, Irving L. Weissman, Matthew A. Inlay.
Stem Cell Reports, (2014), 3(5):707-715.
- Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.
Woodling NS, Wang Q, Priyam PG, Larkin P, Shi J, Johansson JU, Zagol-Ikapitte I, Boutaud O, Andreasson KI.
J Neurosci., (2014), 34(17):5882-94.
- An Integrated Cell Purification and Genomics Strategy Reveals Multiple Regulators of Pancreas Development.
Cecil M. Benitez, Kun Qu, Takuya Sugiyama, Philip T. Pauerstein, Yinghua Liu, Jennifer Tsai, Xueying Gu, Amar Ghodasara, H. Efsun Arda, Jiajing Zhang, Joseph D. Dekker, Haley O. Tucker, Howard Y. Chang, Seung K. Kim.
PLoS Genetics, (2014), 10(10):e1004645.
- m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells.
Pedro J. Batista, Benoit Molinie, Jinkai Wang, Kun Qu, Jiajing Zhang, Lingjie Li, Donna M. Bouley, Ernesto Lujan, Bahareh Haddad, Kaveh Daneshvar, Ava C. Carter, Ryan A. Flynn, Chan Zhou, Kok-Seong Lim, Peter Dedon, Marius Wernig, Alan C. Mullen, Yi Xing, Cosmas C. Giallourakis, Howard Y. Chang.
Cell Stem Cell, (2014).
- Alveolar progenitor and stem cells in lung development, renewal and cancer.
Tushar J. Desai, Douglas G. Brownfield & Mark A. Krasnow.
Nature, (2014), 507:190–194.
- A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma.
Chen R, Khatri P, Mazur PK, Polin M, Zheng Y, Vaka D, Hoang CD, Shrager J, Xu Y, Vicent S, Butte AJ, Sweet-Cordero EA.
Cancer Res., (2014), 74(10):2892-902.
- Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response.
Yaw Adomako-Ankomah, Anjali J. Shastri, Sarah E. Ewald, Moritz Treeck, Jon P. Boyle, John C. Boothroyd.
PLoS Biol, (2014), 12(4):e1001845.
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mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).
Rodgers JT, King KY, Brett JO, Cromie MJ, Charville GW, Maguire KK, Brunson C, Mastey N, Liu L, Tsai CR, Goodell MA, Rando TA.
Nature, (2014), 510(7505):393-6.
- Calcineurin Signaling Regulates Neural Induction through Antagonizing the BMP Pathway.
Cho A, Tang Y, Davila J, Deng S, Chen L, Miller E, Wernig M, Graef IA.
Neuron, (2014), 82(1):109-24.
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Noninvasive in vivo monitoring of tissue-specific global gene expression in humans.
Winston Koh, Wenying Pan, Charles Gawad, H. Christina Fan, Geoffrey A. Kerchner, Tony Wyss-Coray, Yair J. Blumenfeld, Yasser Y. El-Sayed, and Stephen R. Quake.
PNAS, (2014).
- Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition.
Zhang H, Cohen AL, Krishnakumar S, Wapnir IL, Veeriah S, Deng G, Coram MA, Piskun CM, Longacre TA, Herrler M, Frimannsson DO, Telli ML, Dirbas FM, Matin AC, Dairkee SH, Larijani B, Glinsky GV, Bild AH, Jeffrey SS.
Breast Cancer Res., (2014), 16(2):R36.
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Males shorten the life span of C. elegans hermaphrodites via secreted compounds.
Maures T.J., Booth L.N., Benayoun B.A., Izrayelit Y., Schroeder F.C., Brunet A.
Science, (2014) , 343(6170):541-544.
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Transcriptional response of Enterococcus faecalis to sunlight.
Sassoubre LM, Ramsey MM, Gilmore MS, Boehm AB.
J Photochem Photobiol B., (2014), 130:349-56.
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Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency.
Yul W Yang, Ryan A Flynn, Yong Chen, Kun Qu, Bingbing Wan, Kevin C Wang, Ming Lei, Howard Y Chang.
ELife, (2014), 3:e02046.
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Age-Related Modulation of the Effects of Obesity on Gene Expression Profiles of Mouse Bone Marrow and Epididymal Adipocytes.
Liu L.-F., Shen W.-J., Ueno M., Patel S., Azhar S., Kraemer F.B.
PLoS ONE, (2013), 8(8):e72367.
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Hormonal Regulation of MicroRNA Expression in Steroid Producing Cells of the Ovary, Testis and Adrenal Gland.
Hu Z, Shen W-J, Cortez Y, Tang X, Liu L-F, et al.
PLoS ONE, (2013), 8(10):e78040.
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The polyubiquitin gene Ubi-p63E is essential for male meiotic cell cycle progression and germ cell differentiation in Drosophila.
Lu C, Kim J, Fuller MT.
J Cell Sci, (2013), 126:e1.
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Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.
Alejandra Sanjuan-Pla, Iain C. Macaulay, Christina T. Jensen, Petter S. Woll, Tiago C. Luis, Adam Mead, Susan Moore, Cintia Carella, Sahoko Matsuoka, Tiphaine Bouriez Jones, Onima Chowdhury, Laura Stenson, Michael Lutteropp, Joanna C. A. Green, Raffaella Facchini, Hanane Boukarabila, Amit Grover, Adriana Gambardella, Supat Thongjuea, Joana Carrelha, Paul Tarrant, Deborah Atkinson, Sally-Ann Clark, Claus Nerlov & Sten Eirik W. Jacobsen.
Nature, (2013), 502(7470):232-236.
- Targeted Disruption of Hotair Leads to Homeotic Transformation and Gene Derepression.
Lingjie Li, Bo Liu, Orly L. Wapinski, Miao-Chih Tsai, Kun Qu, Jiajing Zhang, Jeff C. Carlson, Meihong Lin, Fengqin Fang, Rajnish A. Gupta, Jill A. Helms, Howard Y. Chang.
Cell Reports, (2013), 5(1):3-12.
- The human oviduct transcriptome reveals an anti-inflammatory, anti-angiogenic, secretory and matrix-stable environment during embryo transit.
A.P. Hess, S. Talbi, A.E. Hamilton, D.M. Baston-Buest, M. Nyegaard, J.C. Irwin, F. Barragan, J.S. Kruessel, A. Germeyer, L.C. Giudice.
Reproductive BioMedicine Online, (2013), 27(4):423-435.
- Suppression of Inflammation with Conditional Deletion of the Prostaglandin E2 EP2 Receptor in Macrophages and Brain Microglia.
Jenny U. Johansson, Suraj Pradhan, Ludmila A. Lokteva, Nathaniel S. Woodling, Novie Ko, Holden D. Brown, Qian Wang, Christina Loh, Egle Cekanaviciute, Marion Buckwalter, Amy B. Manning-Boğ, and Katrin I. Andreasson.
The Journal of Neuroscience, (2013), 33(40):16016-16032.
- Chromatin Modifications as Determinants of Muscle Stem Cell Quiescence and Chronological Aging.
Ling Liu, Tom H. Cheung, Gregory W. Charville, Bernadette Marie Ceniza Hurgo, Tripp Leavitt, Johnathan Shih, Anne Brunet, Thomas A. Rando.
Cell Reports, (2013), 4(1):189-204.
- FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors.
Adam J. Mead, Shabnam Kharazi, Deborah Atkinson, Iain Macaulay, Christian Pecquet, Stephen Loughran, Michael Lutteropp, Petter Woll, Onima Chowdhury, Sidinh Luc, Natalija Buza-Vidas, Helen Ferry, Sally-Ann Clark, Nicolas Goardon, Paresh Vyas, Stefan N. Constantinescu, Ewa Sitnicka, Claus Nerlov, Sten Eirik W. Jacobsen.
Cell Reports, (2013), 3(6):1766-1776.
- Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain.
Rafalski VA, Ho PP, Brett JO, Ucar D, Dugas JC, Pollina EA, Chow LM, Ibrahim A, Baker SJ, Barres BA, Steinman L, Brunet A. Nat
Cell Biol, (2013), 15(6):614-624.
- Control of somatic tissue differentiation by the long non-coding RNA TINCR.
Markus Kretz, Zurab Siprashvili, Ci Chu, Dan E. Webster, Ashley Zehnder, Kun Qu, Carolyn S. Lee, Ross J. Flockhart, Abigail F. Groff, Jennifer Chow, Danielle Johnston, Grace E. Kim, Robert C. Spitale, Ryan A. Flynn, Grace X. Y. Zheng, Subhadra Aiyer, Arjun Raj, John L. Rinn, Howard Y. Chang, and Paul A. Khavari.
Nature, (2013), 493:231–235.
- IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors.
Katherine L Jameson, Pawel K Mazur, Ashley M Zehnder, Jiajing Zhang, Brian Zarnegar, Julien Sage, and Paul A Khavari.
Nature Medicine, (2013), 19:626–630.
- Dicer is selectively important for the earliest stages of erythroid development.
Natalija Buza-Vidas, Valeriu B. Cismasiu, Susan Moore, Adam J. Mead, Petter S. Woll, Michael Lutteropp, Luca Melchiori, Sidinh Luc, Tiphaine Bouriez-Jones, Deborah Atkinson, Donal O'Carroll, Sten Eirik W. Jacobsen, and Claus Nerlov.
Blood, (2012), 120:2412-2416.
- Gene Expression Commons: An Open Platform for Absolute Gene Expression Profiling.
Seita J, Sahoo D, Rossi DJ, Bhattacharya D, Serwold T, et al.
PLoS ONE, (2012), 7(7):e40321.
- Mice lacking the β2 adrenergic receptor have a unique genetic profile before and after focal brain ischaemia.
Robin E White, Curtis Palm, Lijun Xu, Evelyn Ling, Mitchell Ginsburg, Bernie J Daigle, Ruquan Han, Andrew Patterson, Russ B Altman and Rona G Giffard.
ASN NEURO, (2012), 4(5).
- Innate Immune Responses of Drosophila melanogaster Are Altered by Spaceflight.
Oana Marcu, Matthew P. Lera, Max E. Sanchez, Edina Levic, Laura A. Higgins, Alena Shmygelska, Thomas F. Fahlen, Helen Nichol, Sharmila Bhattacharya.
PLoS One, (2011), 6(1):e15361.
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| Real-Time PCR (back to top) |
- Replication initiator DnaA binds at the Caulobacter centromere and enables chromosome segregation.
Paola E. Mera, Virginia S. Kalogeraki, and Lucy Shapiro.
PNAS, (2014), 111(45):16100-16105.
- Adaptive human CDKAL1 variants underlie hormonal response variations at the enteroinsular axis.
Chia Lin Chang, James J Cai, Shang Yu Huang, Po Jen Cheng, Ho Yen Chueh, Sheau Yu Teddy Hsu.
PLoS One, (2014), 15;9(9):e105410.
- Identification of metabolic modifiers that underlie phenotypic variations in energy-balance regulation.
Chang CL, Cai JJ, Cheng PJ, Chueh HY, Hsu SY.
Diabetes, (2011), 60(3):726-734.
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| PyroSequencing (back to top) |
- Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation.
Wong CP, Rinaldi NA, Ho E.
Mol Nutr Food Res., (2015).
- Pyrosequencing: applicability for studying DNA damage-induced mutagenesis.
Irina G. Minko, Lauriel F.Earley, Kimberly E.Larlee, Ying-Chih Lin and R.Stephen Lloyd.
Environmental and Molecular Mutagenesis, (2014), 55(8):601–608.
- Maternal bias and escape from X chromosome imprinting in the midgestation mouse placenta.
Elizabeth H. Finn, Cheryl L. Smith, Jesse Rodriguez, Arend Sidow, Julie C. Baker.
Developmental Biology, (2014), 390(1):80-92.
- Investigation of HOXA9 promoter methylation as a biomarker to distinguish oral cancer patients at low risk of neck metastasis.
Uchida K, Veeramachaneni R, Huey B, Bhattacharya A, Schmidt BL, Albertson DG.
BMC Cancer, (2014), 14:353.
- Effects of Sulforaphane and 3,3′-Diindolylmethane on Genome-Wide Promoter Methylation in Normal Prostate Epithelial Cells and Prostate Cancer Cell.
Carmen P. Wong, Anna Hsu, Alex Buchanan, Zoraya Palomera-Sanchez, Laura M. Beaver, E. Andres Houseman, David E. Williams, Roderick H. Dashwood, Emily Ho.
PLoS One, (2014), 9:e86787.
- Coronary Heart Disease-Associated Variation in TCF21 Disrupts a miR-224 Binding Site and miRNA-Mediated Regulation.
Miller CL, Haas U, Diaz R, Leeper NJ, Kundu RK, et al.
PLoS Genet, (2014), 10(3):e1004263.
- Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
Wang, R., Löhr, C. V., Fischer, K., Dashwood, W. M., Greenwood, J. A., Ho, E., Williams, D. E., Ashktorab, H., Dashwood, M. R. and Dashwood, R. H.
Int. J. Cancer, (2013), 132:1004–1012.
- Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus.
Clint L. Miller mail, D. Ryan Anderson, Ramendra K. Kundu, Azad Raiesdana, Sylvia T. Nürnberg, Roxanne Diaz, Karen Cheng, Nicholas J. Leeper, Chung-Hsing Chen, I-Shou Chang, Eric E. Schadt, Chao Agnes Hsiung, Themistocles L. Assimes, Thomas Quertermous.
PLoS Genetics, (2013), 9(7):e1003652.
- DNA methylome signature in rheumatoid arthritis.
Nakano K, Whitaker JW, Boyle DL, et al.
Ann Rheum Dis, (2013), 72:110-117.
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| Next Generation Sequencing (back to top) |
- A long noncoding RNA protects the heart from pathological hypertrophy.
Pei Han, Wei Li, Chiou-Hong Lin, Jin Yang, Ching Shang, Sylvia T. Nuernberg, Kevin Kai Jin, Weihong Xu, Chieh-Yu Lin, Chien-Jung Lin, Yiqin Xiong, Huan-Chieh Chien, Bin Zhou, Euan Ashley, Daniel Bernstein, Peng-Sheng Chen, Huei-Sheng Vincent Chen, Thomas Quertermous, and Ching-Pin Chang.
Nature, (2014), 514(7520):102-6.
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| DNA Sequencing (Sanger)/Fragment Analysis (back to top) |
- Using Unnatural Amino Acids to Probe the Energetics of Oxyanion Hole Hydrogen Bonds in the Ketosteroid Isomerase Active Site.
Aditya Natarajan , Jason P. Schwans , and Daniel Herschlag.
J. Am. Chem. Soc., (2014), 136(21):7643–7654.
- Vitamin D Receptor Mutations in Patients with Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets.
Peter J. Malloya, Velibor Tasicb, Doris Tahac, Filiz Tütüncülerd, Goh Siok Yinge, Loke Kah Yine, Jining Wanga, David Feldman.
Molecular Genetics and Metabolism, (2014), 111(1):33-40.
- Honey Bees Avoid Nectar Colonized by Three Bacterial Species, But Not by a Yeast Species, Isolated from the Bee Gut.
Ashley P. Good, Marie-Pierre L. Gauthier, Rachel L. Vannette, Tadashi Fukami.
PLoS ONE, (2014), 9(1):e86494.
- Hands and Water as Vectors of Diarrheal Pathogens in Bagamoyo, Tanzania.
Mia Catharine Mattioli, Amy J. Pickering, Rebecca J. Gilsdorf, Jennifer Davis, and Alexandria B. Boehm.
Environmental Science & Technology, (2013), 47 (1):355-363.
- Exome sequencing to identify de novo mutations in sporadic ALS trios.
Alessandra Chesi, Brett T Staahl, Ana Jovičić, Julien Couthouis, Maria Fasolino, Alya R Raphael, Tomohiro Yamazaki, Laura Elias, Meraida Polak, Crystal Kelly, Kelly L Williams, Jennifer A Fifita, Nicholas J Maragakis, Garth A Nicholson, Oliver D King, Robin Reed, Gerald R Crabtree, Ian P Blair, Jonathan D Glass, and Aaron D Gitler.
Nature Neuroscience, (2013), 16(7):851–855.
- Enteral calcium infusion used successfully as treatment for a patient with hereditary vitamin D resistant rickets (HVDRR) without alopecia: a novel mutation.
Huang K, Malloy P, Feldman D, Pitukcheewanont P.
Gene, (2013), 512(2):554-559.
- Structural Map of a MicroRNA-122: Hepatitis C Virus Complex.
Pang, Phillip S.; Pham, Edward A.; Elazar, Menashe; et al.
JOURNAL OF VIROLOGY, (2012), 86(2):1250-1254.
- Influence of 17β-estradiol on gene expression of paracoccidioides during mycelia-to-yeast transition.
Shankar J., Wu T.D., Clemons K.V., Monteiro J.P., Mirels L.F., Stevens D.A.
PLoS ONE, (2011), 6(12):e28402.
- A synthetic library of RNA control modules for predictable tuning of gene expression in yeast.
Babiskin AH, Smolke CD.
Mol Syst Biol, (2011), 7:471.
- Simplified RNA secondary structure mapping by automation of SHAPE data analysis.
Pang PS, Elazar M, Pham EA, Glenn JS.
Nucleic Acids Res, (2011), 39(22):e151.
- Hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from a novel missense mutation in the DNA-binding domain of the vitamin D receptor.
Malloy PJ, Wang J, Srivastava T, Feldman D.
Mol Genet Metab, (2010), 99(1):72-79.
- Hereditary vitamin D resistant rickets: identification of a novel splice site mutation in the vitamin D receptor gene and successful treatment with oral calcium therapy.
Ma NS, Malloy PJ, Pitukcheewanont P, Dreimane D, Geffner ME, Feldman D.
Bone, (2009), 45(4):743-746.
- Phase variation and microevolution at homopolymeric tracts in Bordetella pertussis.
Gogol EB, Cummings CA, Burns RC, Relman DA.
BMC Genomics, (2007), 8:122.
- Growth of a Dehalococcoides-like microorganism on vinyl chloride and cis-dichloroethene as electron acceptors as determined by competitive PCR.
Cupples AM, Spormann AM, McCarty PL.
Appl Environ Microbiol, (2003), 69(2):953-959.
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| Peptide Synthesis (back to top) |
- Apela regulates fluid homeostasis by binding to the APJ receptor to activate Gi signaling.
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| Mass Spectrometry (back to top) |
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Metabolic Engineering, (2014), 22:60–68.
- Engineering agatoxin, a cystine-knot Peptide from spider venom, as a molecular probe for in vivo tumor imaging.
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PloS One, (2013), 8:e60498.
- Engineered knottin peptide enables noninvasive optical imaging of intracranial medulloblastoma.
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| Protein Analytics - Mass Mapping/Edman Sequencing (back to top) |
- Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains.
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Structural and Functional Modularity of the Orange Carotenoid Protein: Distinct Roles for the N- and C-Terminal Domains in Cyanobacterial Photoprotection.
Ryan L. Leverenz, Denis Jallet, Ming-De Li, Richard A. Mathies, Diana Kirilovsky, and Cheryl A. Kerfeld.
The Plant Cell, (2014), 26(1):426-437.
- Engineered knottin peptide enables noninvasive optical imaging of intracranial medulloblastoma.
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- Engineering Agatoxin, a cystine-knot peptide from spider venom, as a molecular probe for in vivo tumor imaging.
Moore, S. J., Leung, C. L., Norton, H.K., and Cochran, J. R..
PLoS ONE, (2013), 8:e60498.
- Defective Autoimmune Regulator-Dependent Central Tolerance to Myelin Protein Zero Is Linked to Autoimmune Peripheral Neuropathy.
Maureen A., Davini, Dan, Cheng, Philip, et al.
JOURNAL OF IMMUNOLOGY, (2012), 188(10):4906-4912.
- Purification, characterization and cloning of tensilin, the collagen-fibril binding and tissue-stiffening factor from Cucumaria frondosa dermis.
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- Molecular characterization and antibody detection of a nitrogen-regulated cell-surface protein of the coccolithophore Emiliania Huxleyi (Prymnesiophyceae).
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| Surface Plasmon Resonance (Biacore) (back to top) |
- The Structural Basis of Substrate Recognition by the Eukaryotic Chaperonin TRiC/CCT.
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Structure, (2013), 21(9):1590-1601.
- ALIX is a Lys63-specific polyubiquitin binding protein that functions in retrovirus budding.
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- A versatile cis-blocking and trans-activation strategy for ribozyme characterization.
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- Antagonistic VEGF variants engineered to simultaneously bind to and inhibit VEGFR2 and αvβ3 integrin.
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- The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins.
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- Quantification of protein interactions and solution transport using high-density GMR sensor arrays.
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- A spindle-like apparatus guides bacterial chromosome segregation.
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