The Stanford Center for Innovation in In Vivo Imaging (Sci3) is a small animal imaging facility that allows non-invasive studies on animals such as mice and rats. In addition to instruments routinely used in the clinic, such as ultrasound, microCT, microPET, microSPECT/CT, and MRI (each optimized for animal research), the facility also has instruments to investigate bio-distribution of molecular imaging probes such as GFP, fluorescent markers and bioluminescent proteins in these animals. Access to surgical benches and supplies is available. Instrument training is provided for free during regular sessions, which are posted through an email service. In addition, full computer support and data archiving is provided to investigators.
Available Equipment
- Macrotome
- microSPECT/CT
- Microtome
- Ultrasound
- MRI
- Computer/Administration Area
- PIM
- IVIS
- Cellvizio
- Maestro
- Time-domain fluorescence Imagers
- Login Computer
- microCT
- PAM
- microPET
- microPET-CT
Selected References
Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture. Gilbert PM, Havenstrite KL, Magnusson KE, et al. Science; 329(5995): p. 1078-81. PubMedID: 20647425; PMCID: PMC2929271
Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. Lee JH, Durand R, Gradinaru V, et al. Nature; 465(7299): p. 788-92. PubMedID: 2047328; PMCID: PMC3177305
Fgf-9 is required for angiogenesis and osteogenesis in long bone repair. Behr B, Leucht P, Longaker MT, et al. Proc Natl Acad Sci U S A; 107(26): p. 11853-8. PubMedID: 20547837; PMCID: PMC2900703.