Publications

• Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure
  Perez, M. V., Pavlovic, A., Shang, C., Wheeler, M. T., Miller, C. L., & Ashley, E. A. (2015). Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 66(22), 2522-2533.
• Long-Term Prognosis of Early Repolarization With J-Wave and QRS Slur Patterns on the Resting Electrocardiogram: A Cohort Study.
  Pargaonkar, V. S., Perez, M. V., Jindal, A., Mathur, M. B., Myers, J., & Froelicher, V. F. (2015). Long-Term Prognosis of Early Repolarization With J-Wave and QRS Slur Patterns on the Resting Electrocardiogram: A Cohort Study. Annals of internal medicine, 163(10), 747-755.
• Gender Differences in Ventricular Remodeling and Function in College Athletes, Insights from Lean Body Mass Scaling and Deformation Imaging
  Giraldeau, G., Kobayashi, Y., Finocchiaro, G., Wheeler, M., Perez, M., & Haddad, F. (2015). Gender Differences in Ventricular Remodeling and Function in College Athletes, Insights from Lean Body Mass Scaling and Deformation Imaging. AMERICAN JOURNAL OF CARDIOLOGY, 116(10), 1610-1616.
• Limitations of Current AHA Guidelines and Proposal of New Guidelines for the Preparticipation Examination of Athletes Dunn, T. P., Pickham, D., Aggarwal, S., Saini, D., Kumar, N., & Froelicher, V. F. (2015). Limitations of Current AHA Guidelines and Proposal of New Guidelines for the Preparticipation Examination of Athletes. CLINICAL JOURNAL OF SPORT MEDICINE, 25(6), 472-477.
  
• Reply to van Oosten et al: "P-Wave Characteristics on Routine Preoperative Electrocardiogram Improve Prediction of New-Onset Postoperative Atrial Fibrillation in Cardiac Surgery". Wong, J. K., Maxwell, B. G., & Perez, M. V. (2015). Reply to van Oosten et al: "P-Wave Characteristics on Routine Preoperative Electrocardiogram Improve Prediction of New-Onset Postoperative Atrial Fibrillation in Cardiac Surgery". Journal of cardiothoracic and vascular anesthesia, 29(5), e63-4.
  
• Systematic Comparison of Digital Electrocardiograms From Healthy Athletes and Patients With Hypertrophic Cardiomyopathy. Bent, R. E., Wheeler, M. T., Hadley, D., Knowles, J. W., Pavlovic, A., & Perez, M. V. (2015). Systematic Comparison of Digital Electrocardiograms From Healthy Athletes and Patients With Hypertrophic Cardiomyopathy. Journal of the American College of Cardiology, 65(22), 2462-2463.
  
• Feasibility of Extended Ambulatory Electrocardiogram Monitoring to Identify Silent Atrial Fibrillation in High-risk Patients: The Screening Study for Undiagnosed Atrial Fibrillation (STUDY-AF) Turakhia, M. P., Ullal, A. J., Hoang, D. D., Than, C. T., Miller, J. D., & Heidenreich, P. A. (2015). Feasibility of Extended Ambulatory Electrocardiogram Monitoring to Identify Silent Atrial Fibrillation in High-risk Patients: The Screening Study for Undiagnosed Atrial Fibrillation (STUDY-AF). CLINICAL CARDIOLOGY, 38(5), 285-292.
  
• Computerized Q wave dimensions in athletes and hypertrophic cardiomyopathy patients Bent, R. E., Wheeler, M. T., Hadley, D., Froelicher, V., Ashley, E., & Perez, M. V. (2015). Computerized Q wave dimensions in athletes and hypertrophic cardiomyopathy patients. JOURNAL OF ELECTROCARDIOLOGY, 48(3), 362-367.
  
• Race and ethnicity, obesity, metabolic health, and risk of cardiovascular disease in postmenopausal women. Schmiegelow, M. D., Hedlin, H., Mackey, R. H., Martin, L. W., Vitolins, M. Z., & Hlatky, M. A. (2015). Race and ethnicity, obesity, metabolic health, and risk of cardiovascular disease in postmenopausal women. Journal of the American Heart Association, 4(5).
  
• Cardiopulmonary responses and prognosis in hypertrophic cardiomyopathy: a potential role for comprehensive noninvasive hemodynamic assessment. Finocchiaro, G., Haddad, F., Knowles, J. W., Caleshu, C., Pavlovic, A., & Ashley, E. A. (2015). Cardiopulmonary responses and prognosis in hypertrophic cardiomyopathy: a potential role for comprehensive noninvasive hemodynamic assessment. JACC. Heart failure, 3(5), 408-418.
  
• Lean body mass and risk of incident atrial fibrillation in post-menopausal women. Azarbal, F., Stefanick, M. L., Assimes, T. L., Manson, J. E., Bea, J. W., & Perez, M. V. (2015). Lean body mass and risk of incident atrial fibrillation in post-menopausal women. European heart journal.
  
• Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis. Shiffman, D., Perez, M. V., Bare, L. A., Louie, J. Z., Arellano, A. R., & Devlin, J. J. (2015). Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis. BMC cardiovascular disorders, 15(1), 104-?.
  
• P-Wave Characteristics on Routine Preoperative Electrocardiogram Improve Prediction of New-Onset Postoperative Atrial Fibrillation in Cardiac Surgery Wong, J. K., Lobato, R. L., Pinesett, A., Maxwell, B. G., Mora-Mangano, C. T., & Perez, M. V. (2014). P-Wave Characteristics on Routine Preoperative Electrocardiogram Improve Prediction of New-Onset Postoperative Atrial Fibrillation in Cardiac Surgery. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 28(6), 1497-1504.
  
• Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval Seyerle, A. A., Young, A. M., Jeff, J. M., Melton, P. E., Jorgensen, N. W., & Avery, C. L. (2014). Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval. EPIDEMIOLOGY, 25(6), 790-798.
  
• Molecular diagnosis of long QT syndrome at 10 days of life by rapid whole genome sequencing. Priest, J. R., Ceresnak, S. R., Dewey, F. E., Malloy-Walton, L. E., Dunn, K., & Ashley, E. A. (2014). Molecular diagnosis of long QT syndrome at 10 days of life by rapid whole genome sequencing. Heart rhythm , 11(10), 1707-1713.
  
• Association Between Success Rate and Citation Count of Studies of Radiofrequency Catheter Ablation for Atrial Fibrillation Possible Evidence of Citation Bias Perino, A. C., Hoang, D. D., Holmes, T. H., Santangeli, P., Heidenreich, P. A., & Turakhia, M. P. (2014). Association Between Success Rate and Citation Count of Studies of Radiofrequency Catheter Ablation for Atrial Fibrillation Possible Evidence of Citation Bias. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 7(5), 687-692.
  
• Obesity, physical activity, and their interaction in incident atrial fibrillation in postmenopausal women. Azarbal, F., Stefanick, M. L., Salmoirago-Blotcher, E., Manson, Ja. E., Albert, C. M., & Perez, M. V. (2014). Obesity, physical activity, and their interaction in incident atrial fibrillation in postmenopausal women. Journal of the American Heart Association, 3(4).
  
• Exercise capacity and paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy Azarbal, F., Singh, M., Finocchiaro, G., Vy-Van Le, V. V., Schnittger, I., & Perez, M. (2014). Exercise capacity and paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy. HEART, 100(8), 624-630.
  
• Latent Obstruction and Left Atrial Size Are Predictors of Clinical Deterioration Leading to Septal Reduction in Hypertrophic Cardiomyopathy Finocchiaro, G., Haddad, F., Pavlovic, A., Sinagra, G., Schnittger, I., & Ashley, E. (2014). Latent Obstruction and Left Atrial Size Are Predictors of Clinical Deterioration Leading to Septal Reduction in Hypertrophic Cardiomyopathy. JOURNAL OF CARDIAC FAILURE, 20(4), 236-243.
  
• Patterns and prognosis of all components of the J-wave pattern in multiethnic athletes and ambulatory patients Muramoto, D., Yong, C. M., Singh, N., Aggarwal, S., Perez, M., & Froelicher, V. (2014). Patterns and prognosis of all components of the J-wave pattern in multiethnic athletes and ambulatory patients. AMERICAN HEART JOURNAL, 167(2), 259-266.
  
• Prevalence and Clinical Correlates of Right Ventricular Dysfunction in Patients With Hypertrophic Cardiomyopathy Finocchiaro, G., Knowles, J. W., Pavlovic, A., Perez, M., Magavern, E., & Ashley, E. A. (2014). Prevalence and Clinical Correlates of Right Ventricular Dysfunction in Patients With Hypertrophic Cardiomyopathy. AMERICAN JOURNAL OF CARDIOLOGY, 113(2), 361-367.
  
• Use of Medicare data to identify coronary heart disease outcomes in the Women's Health Initiative. Hlatky, M. A., Ray, R. M., Burwen, D. R., Margolis, K. L., Johnson, K. C., & Stefanick, M. L. (2014). Use of Medicare data to identify coronary heart disease outcomes in the Women's Health Initiative. Circulation. Cardiovascular quality and outcomes, 7(1), 157-162.
  
• Electrocardiographic Repolarization-Related Variables as Predictors of Coronary Heart Disease Death in the Women's Health Initiative Study. Rautaharju, P. M., Zhang, Z.-M., Vitolins, M., Perez, M., Allison, M. A., & Soliman, E. Z. (2014). Electrocardiographic Repolarization-Related Variables as Predictors of Coronary Heart Disease Death in the Women's Health Initiative Study. Journal of the American Heart Association, 3(4).
  
• Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval. Seyerle, A. A., Young, A. M., Jeff, J. M., Melton, P. E., Jorgensen, N. W., & Avery, C. L. (2014). Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval. Epidemiology (Cambridge, Mass.), 25(6), 790-8.
  
• Does CHA2DS2-VASc improve stroke risk stratification in postmenopausal women with atrial fibrillation? Abraham, Je. M., Larson, J., Chung, M. K., Curtis, A. B., Lakshminarayan, K., & Wassertheil-Smoller, S. (2013). Does CHA2DS2-VASc improve stroke risk stratification in postmenopausal women with atrial fibrillation?. American journal of medicine, 126(12), 1143 e1-8.
  
• Variation in Use of Left Ventriculography in the Veterans Affairs Health Care System Heidenreich, P. A., Lin, S., Knowles, J. W., Perez, M., Maddox, T. M., & Witteles, R. M. (2013). Variation in Use of Left Ventriculography in the Veterans Affairs Health Care System. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 6(6), 687-693.
  
• Prognostic implications of the J wave ECG patterns Yong, C. M., Perez, M., & Froelicher, V. (2013). Prognostic implications of the J wave ECG patterns. JOURNAL OF ELECTROCARDIOLOGY, 46(5), 408-410.
  
• African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative. Perez, M. V., Hoffmann, T. J., Tang, H., Thornton, T., Stefanick, M. L., & Risch, N. (2013). African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative. American heart journal, 166(3), 566-572.
  
• J wave patterns and their prognostic value in African Americans Perez, M. V., & Froelicher, V. (2013). J wave patterns and their prognostic value in African Americans. JOURNAL OF ELECTROCARDIOLOGY, 46(5), 442-445.
  
• Risk factors for atrial fibrillation and their population burden in postmenopausal women: the Women's Health Initiative Observational Study Perez, M. V., Wang, P. J., Larson, J. C., Soliman, E. Z., Limacher, M., & Stefanick, M. L. (2013). Risk factors for atrial fibrillation and their population burden in postmenopausal women: the Women's Health Initiative Observational Study. HEART, 99(16), 1173-1178.
  
• Different patterns of bundle-branch blocks and the risk of incident heart failure in the Women's Health Initiative (WHI) study. Zhang, Z.-M., Rautaharju, P. M., Soliman, E. Z., Manson, Ja. E., Martin, L. W., & Prineas, R. J. (2013). Different patterns of bundle-branch blocks and the risk of incident heart failure in the Women's Health Initiative (WHI) study. Circulation. Heart failure, 6(4), 655-661.
  
• Taming Rare Variation With Known Biology in Long QT Syndrome. Perez, M. V., & Ashley, E. A. (2013). Taming Rare Variation With Known Biology in Long QT Syndrome. Circulation. Cardiovascular genetics, 6(3), 227-229.
  
• From bedside to bench Perez, M., & Froelicher, V. (2013). From bedside to bench. JOURNAL OF ELECTROCARDIOLOGY, 46(2), 114-115.
  
• Pacemaker Therapy in Atrial Fibrillation Park, S., Wang, P. J., Zei, P. C., Hsia, H. H., Turakhi, M., & Al-Ahmad, A. A. (2013). Pacemaker Therapy in Atrial Fibrillation. Journal of Cardiology and Vascular Medicine, 1.
  
• Effects of Postmenopausal Hormone Therapy on Incident Atrial Fibrillation The Women's Health Initiative Randomized Controlled Trials Perez, M. V., Wang, P. J., Larson, J. C., Virnig, B. A., Cochrane, B., & Stefanick, M. L. (2012). Effects of Postmenopausal Hormone Therapy on Incident Atrial Fibrillation The Women's Health Initiative Randomized Controlled Trials. CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 5(6), 1108-1116.
  
• Semantic Confusion: The Case of Early Repolarization and the J Point Perez, M. V., Friday, K., & Froelicher, V. (2012). Semantic Confusion: The Case of Early Repolarization and the J Point. AMERICAN JOURNAL OF MEDICINE, 125(9), 843-844.
  
• Prognostic Implications of Q Waves and T-Wave Inversion Associated With Early Repolarization Uberoi, A., Sallam, K., Perez, M., Jain, N. A., Ashley, E., & Froelicher, V. (2012). Prognostic Implications of Q Waves and T-Wave Inversion Associated With Early Repolarization. MAYO CLINIC PROCEEDINGS, 87(7), 614-619.
  
• Use and overuse of left ventriculography Witteles, R. M., Knowles, J. W., Perez, M., Morris, W. M., Spettell, C. M., & Heidenreich, P. A. (2012). Use and overuse of left ventriculography. AMERICAN HEART JOURNAL, 163(4), 617-?.
  
• The prognostic value of early repolarization with ST-segment elevation in African Americans Perez, M. V., Uberoi, A., Jain, N. A., Ashley, E., Turakhia, M. P., & Froelicher, V. (2012). The prognostic value of early repolarization with ST-segment elevation in African Americans. HEART RHYTHM, 9(4), 558-565.
  
• Catheter ablation of atrial fibrillation: state-of-the-art techniques and future perspectives Santangeli, P., Di Biase, L., Burkhardt, D. J., Horton, R., Sanchez, J., & Al-Ahmad, A. (2012). Catheter ablation of atrial fibrillation: state-of-the-art techniques and future perspectives. JOURNAL OF CARDIOVASCULAR MEDICINE, 13(2), 108-124.
  
• Early Repolarization in an Ambulatory Clinical Population Uberoi, A., Jain, N. A., Perez, M., Weinkopff, A., Ashley, E., & Froelicher, V. (2011). Early Repolarization in an Ambulatory Clinical Population. CIRCULATION, 124(20), 2208-2214.
  
• The Impact of ST Elevation on Athletic Screening Leo, T., Uberoi, A., Jain, N. A., Garza, D., Chowdhury, S., & Froelicher, V. (2011). The Impact of ST Elevation on Athletic Screening. CLINICAL JOURNAL OF SPORT MEDICINE, 21(5), 433-440.
  
• Interpretation of the Electrocardiogram of Young Athletes Uberoi, A., Stein, R., Perez, M. V., Freeman, J., Wheeler, M., & Froelicher, V. (2011). Interpretation of the Electrocardiogram of Young Athletes. CIRCULATION, 124(6), 746-757.
  
• Gene Coexpression Network Topology of Cardiac Development, Hypertrophy, and Failure Dewey, F. E., Perez, M. V., Wheeler, M. T., Watt, C., Spin, J., & Ashley, E. A. (2011). Gene Coexpression Network Topology of Cardiac Development, Hypertrophy, and Failure. CIRCULATION-CARDIOVASCULAR GENETICS, 4(1), 26-U129.
  
• Personalized Medicine and Cardiovascular Disease: From Genome to Bedside S. Pan, F. E. Dewey, M. V. Perez, J. W. Knowles, R. Chen, & E. A. Ashley. (2011). Personalized Medicine and Cardiovascular Disease: From Genome to Bedside. Current Cardiovascular Risk Reports, 5.
  
• Cost-Effectiveness of Genetic Testing in Family Members of Patients With Long-QT Syndrome Perez, M. V., Kumarasamy, N. A., Owens, D. K., Wang, P. J., & Hlatky, M. A. (2011). Cost-Effectiveness of Genetic Testing in Family Members of Patients With Long-QT Syndrome. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 4(1), 76-84.
  
• Inappropriate pacing in a patient with managed ventricular pacing: What is the cause? Perez, M. V., Al-Ahmad, A. A., Wang, P. J., & Turakhia, M. P. (2010). Inappropriate pacing in a patient with managed ventricular pacing: What is the cause?. HEART RHYTHM, 7(9), 1336-1337.
  
• Addition of the Electrocardiogram to the Preparticipation Examination of College Athletes Le, V.-V., Wheeler, M. T., Mandic, S., Dewey, F., Fonda, H., & Froelicher, V. (2010). Addition of the Electrocardiogram to the Preparticipation Examination of College Athletes. CLINICAL JOURNAL OF SPORT MEDICINE, 20(2), 98-105.
  
• Adding an Electrocardiogram to the Pre-participation Examination in Competitive Athletes: A Systematic Review Perez, M., Fonda, H., Le, V.-V., Mitiku, T., Ray, J., & Froelicher, V. F. (2009). Adding an Electrocardiogram to the Pre-participation Examination in Competitive Athletes: A Systematic Review. CURRENT PROBLEMS IN CARDIOLOGY, 34(12), 586-662.
  
• Electrocardiographic predictors of atrial fibrillation Perez, M. V., Dewey, F. E., Marcus, R., Ashley, E. A., Al-Ahmad, A. A., & Froelicher, V. F. (2009). Electrocardiographic predictors of atrial fibrillation. AMERICAN HEART JOURNAL, 158(4), 622-628.
  
• Mechanisms of exercise intolerance in patients with hypertrophic cardiomyopathy Le, V.-V., Perez, M. V., Wheeler, M. T., Myers, J., Schnittger, I., & Ashley, E. A. (2009). Mechanisms of exercise intolerance in patients with hypertrophic cardiomyopathy. AMERICAN HEART JOURNAL, 158(3), E27-E34.
  
• Statin Use and Ventricular Arrhythmias During Clinical Treadmill Testing Dewey, F. E., Perez, M., Hadley, D., Freeman, J. V., Wang, P., & Froelicher, V. F. (2009). Statin Use and Ventricular Arrhythmias During Clinical Treadmill Testing. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 20(2), 193-199.
  
• Added Value of a Resting ECG Neural Network That Predicts Cardiovascular Mortality Perez, M. V., Dewey, F. E., Tan, S. Y., Myers, J., & Froelicher, V. F. (2009). Added Value of a Resting ECG Neural Network That Predicts Cardiovascular Mortality. ANNALS OF NONINVASIVE ELECTROCARDIOLOGY, 14(1), 26-34.
  
• Isolated Disease of the Proximal Left Anterior Descending Artery Comparing the Effectiveness of Percutaneous Coronary Interventions and Coronary Artery Bypass Surgery Kapoor, J. R., Gienger, A. L., Ardehali, R., Varghese, R., Perez, M. V., & Bravata, D. M. (2008). Isolated Disease of the Proximal Left Anterior Descending Artery Comparing the Effectiveness of Percutaneous Coronary Interventions and Coronary Artery Bypass Surgery. JACC-CARDIOVASCULAR INTERVENTIONS, 1(5), 483-491.
  
• Genetics of Arrhythmia: Disease Pathways Beyond Ion Channels Perez, M. V., Wheeler, M., Ho, M., Pavlovic, A., Wang, P., & Ashley, E. A. (2008). Genetics of Arrhythmia: Disease Pathways Beyond Ion Channels. JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 1(2), 155-165.
  
• Systematic review: The comparative effectiveness of percutaneous coronary interventions and coronary artery bypass graft surgery Bravata, D. M., Gienger, A. L., McDonald, K. M., Sundaram, V., Perez, M. V., & Hlatky, M. A. (2007). Systematic review: The comparative effectiveness of percutaneous coronary interventions and coronary artery bypass graft surgery. ANNALS OF INTERNAL MEDICINE, 147(10), 703-U139.
  
• Prognostic value of the computerized ECG in Hispanics Perez, M. V., Yaw, T. S., Myers, J., & Froelicher, V. F. (2007). Prognostic value of the computerized ECG in Hispanics. CLINICAL CARDIOLOGY, 30(4), 189-194.
  
• Giant coronary aneurysms in heart transplantation: an unusual presentation of cardiac allograft vasculopathy Haddad, F., Perez, M., Fleischmann, D., Valantine, H., & Hunt, S. A. (2006). Giant coronary aneurysms in heart transplantation: an unusual presentation of cardiac allograft vasculopathy. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 25(11), 1367-1370.
  
• p300/MDM2 complexes participate in MDM2-mediated p53 degradation Grossman, S. R., Perez, M., Kung, A. L., Joseph, M., Mansur, C., & Livingston, D. M. (1998). p300/MDM2 complexes participate in MDM2-mediated p53 degradation. MOLECULAR CELL, 2(4), 405-415.