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Stanford:
functional genomics facility
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| Tools for capturing the functional state of
a cell or collection of cells have advanced rapidly in the last
decade. Prominent among these are a variety of DNA microarray
technologies. In particular, complementary DNA microarrays have made
it practical to inexpensively quantify the expression of thousands of
genes in parallel. This mode of analysis has been used to observe gene
expression variation in a variety of human tumors and other tissue as
well as a number of single cell organisms and plants. We intend to
provide a facility whereby Stanford medical and other researchers have
easy access to the most advanced functional genomic technologies at
nominal cost. Researchers will be able to access the facility at a
number of levels. At the highest service level, clinical researchers
can submit tissue and have results on the relative expression or
protein level functional state of the sample returned to them. If more
control is desired, the researcher can join in the process at any
number of points, all the way down to collaborating with the facility
on protocol and instrumentation development. The Functional Genomics
Facility will provide an environment where biologists and engineers
can work together. Because of the rapidly evolving nature of the
underlying technologies, a core facility with strong academic ties
will be in a good position to innovate or take advantage of
innovation. The facility will be guided in its development by
experimenters needs and not by any particular technology choice.
However, we do anticipate using the progress made in the production of
low cost cDNA microarrays to be a well-defined launching point for the
facility.
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| © 2008 Copyright The Board of Trustees of Leland Stanford Junior University
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All Rights
Reserved
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