An Evaluation of High-Throughput Approaches to QTL Mapping in Saccharomyces cerevisiae. Wilkening, S., Lin, G., Fritsch, E.S., Tekkedil, M.M., Anders, S., Kuehn, R., Nguyen, M., Aiyar, R.S., Proctor, M., Sakhanenko, N.A., Galas, D.J., Gagneur, J., Deutschbauer, A. & Steinmetz, L.M. Genetics (2013) PubMed | DOI
Genotype-environment interactions reveal causal pathways that mediate genetic effects on phenotype. Gagneur, J., Stegle, O., Zhu, C., Jakob, J., Tekkedil, M.M., Aiyar, R.S., Schuon, A.K., Pe’er, D. & Steinmetz, L.M. PLoS Genetics (2013) PubMed | DOI
Extensive transcriptional heterogeneity revealed by isoform profiling. Pelechano, V., Wei, W. & Steinmetz, L.M. Nature (2013) Apr 24. PubMed | DOI
The Genomic and Transcriptomic Landscape of a HeLa Cell Line. Landry, J.J., Pyl, P.T., Rausch, T., Zichner, T., Tekkedil, M.M., Stütz, A.M., Jauch, A., Aiyar, R.S., Pau, G., Delhomme, N., Gagneur, J., Korbel, J.O., Huber, W. & Steinmetz, L.M. G3: Genes | Genomes | Genetics (2013) Mar 26. PubMed | DOI
Experimental relocation of the mitochondrial ATP9 gene to the nucleus reveals forces underlying mitochondrial genome evolution. Bietenhader, M., Martos, A., Tetaud, E., Aiyar, R.S., Sellem, C., Kucharczyk, R., Clauder-Muenster, S., Giraud, M.F., Godard, F., Salin, B., Sagot, I., Gagneur, J., Dequard-Chablat, M., Contamine, V., Hermann-Le Denmat, S., Sainsard-Chanet, A., Steinmetz, L.M.* & di Rago, J.P.* PLoS Genet. (2012) Aug 16. PubMed | DOI
Antisense expression increases gene expression variability and locus interdependency. Xu, Z., Wei, W., Gagneur, J., Clauder-Muenster, S., Smolik, M., Huber, W. & Steinmetz, L.M. Mol. Systems Biology (2011) Feb 15;7:468. PubMed | DOI | F1000 Evaluation
Dissecting the genetic basis of resistance to malaria parasites in Anopheles gambiae. Blandin, S.A., Wang-Sattler, R., Lamacchia, M., Gagneur, J., Lycett, G., Ning, Y., Levashina, E.A. & Steinmetz, L.M. Science (2009) 326:147–150. PubMed | DOI
Bidirectional promoters generate pervasive transcription in yeast. Xu, Z., Wei, W., Gagneur, J., Perocchi, F., Clauder-Muenster, S., Camblong, J., Guffanti, E., Stutz, F., Huber, W., & Steinmetz, L.M. Nature (2009) 457, 1033–1037. PubMed | DOI
High-resolution mapping of meiotic crossovers and noncrossovers in yeast. Mancera, E., Bourgon, R., Brozzi, A., Huber, W. & Steinmetz, L.M. Nature 454, 479–485 (2008). PubMed | DOI | F1000 Evaluation
A high-resolution map of transcription in the yeast genome. David, L., Huber, W., Granovskaia, M., Toedling, J., Palm, C. J., Bofkin, L., Jones, T., Davis R.W. & Steinmetz, L.M. Proc. Natl. Acad. Sci. USA (2006) 103, 5320–5325. PubMed | DOI | F1000 Evaluation