"Studying Systemic Lupus in Sweden: Pros and Cons of Register-based Data in the Setting of a Chronic Disease"

Please note: All research in progress seminars are off-the-record. Any information about methodology and/or results is embargoed until publication.

Abstract

National registers such as the Scandinavian Health Registers are often viewed as a holy grail. These types of data have been used for decades, predating the big data buzz. While the population-based nature of these data overcome many methodologic challenges regarding appropriate control selection, representativeness, generalizability, and statistical power, their limitations should be equally acknowledged. Using a current national register linkage across nearly one dozen Swedish registers, this talk will highlight obstacles and benefits in the setting of reproductive and perinatal outcomes in systemic lupus erythematosus (SLE), a chronic inflammatory disease.