Plasmacytoma
Definition
- Clonal plasma cell proliferation that is immunophenotypically and cytologically identical to plasma cell myeloma, but manifests as localized disease
Diagnostic Criteria
- Osseous plasmacytoma/solitary plasmacytoma of bone
- Solitary lytic bone lesion consisting of clonal plasma cells
- No evidence of plasmacytosis in other bone marrow sites or clinical features of plasma cell myeloma (renal insufficiency/ anemia/ hypercalcemia/ additional lesions on skeletal survey)
- Extraosseous plasmacytoma
- Extraosseous/extramedullary mass of neoplastic plasma cells
- No evidence of plasmacytosis in other bone marrow sites or clinical features of plasma cell myeloma (renal insufficiency/ anemia/ hypercalcemia/ additional lesions on skeletal survey)
Dita Gratzinger MD PhD
Department of Pathology
Stanford University School of Medicine
Stanford CA 94305-5342
Initial posting/updates : 9/1/07, 4/15/10
