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Lawrence Recht, MD
Neuro-oncologist
Practice Areas
Professional Education
- Fellowship: Memorial Sloan-Kettering Cancer Center (1984) NY
- Residency: University of Minnesota School of Medicine (1979) MN
- Board Certification: Neurology, American Board of Psychiatry and Neurology (1983)
- Residency: New York Presbyterian Hospital (1982) NY
- Internship: University of Minnesota School of Medicine (1978) MN
- Medical Education: Columbia Presbyterian Medical Center (1977) NY
- M.D., Columbia College of P&S, Medicine (1977)
Publications
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Central Nervous System Cancers Clinical Practice Guidelines in Oncology
Nabors, L. B., Ammirati, M., Bierman, P. J., Brem, H., Butowski, N., & Ho, M. (2013). Central Nervous System Cancers Clinical Practice Guidelines in Oncology. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 11(9), 1114-1151. -
Simultaneous perfusion and permeability measurements using combined spin- and gradient-echo MRI
Schmiedeskamp, H., Andre, J. B., Straka, M., Christen, T., Nagpal, S., & Bammer, R. (2013). Simultaneous perfusion and permeability measurements using combined spin- and gradient-echo MRI. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 33(5), 732-743. -
Metabolic response of glioma to dichloroacetate measured in vivo by hyperpolarized C-13 magnetic resonance spectroscopic imaging
Park, J. M., Recht, L. D., Josan, S., Merchant, M., Jang, T., & Mayer, D. (2013). Metabolic response of glioma to dichloroacetate measured in vivo by hyperpolarized C-13 magnetic resonance spectroscopic imaging. NEURO-ONCOLOGY, 15(4), 433-441. -
ETIRINOTECAN PEGOL DNA Topoisomerase 1 Inhibitor Oncolytic
Nagpal, S., & Recht, L. D. (2013). ETIRINOTECAN PEGOL DNA Topoisomerase 1 Inhibitor Oncolytic. DRUGS OF THE FUTURE, 38(4), 227-233.
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Steroid-Sparing Effect of Corticorelin Acetate in Peritumoral Cerebral Edema Is Associated With Improvement in Steroid-Induced Myopathy
Recht, L., Mechtler, L. L., Wong, E. T., O'Connor, P. C., & Rodda, B. E. (2013). Steroid-Sparing Effect of Corticorelin Acetate in Peritumoral Cerebral Edema Is Associated With Improvement in Steroid-Induced Myopathy. JOURNAL OF CLINICAL ONCOLOGY, 31(9), 1182-1187.
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Thrombin-cleaved Fragments of Osteopontin Are Overexpressed in Malignant Glial Tumors and Provide a Molecular Niche with Survival Advantage
Yamaguchi, Y., Shao, Z., Sharif, S., Du, X.-Y., Myles, T., & Leung, L. Lk. (2013). Thrombin-cleaved Fragments of Osteopontin Are Overexpressed in Malignant Glial Tumors and Provide a Molecular Niche with Survival Advantage. JOURNAL OF BIOLOGICAL CHEMISTRY, 288(5), 3097-3111.
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Advances in the management of glioblastoma: the role of temozolomide and MGMT testing.
Thomas, R. P., Recht, L., & Nagpal, S. (2013). Advances in the management of glioblastoma: the role of temozolomide and MGMT testing. Clinical pharmacology : advances and applications, 5, 1-9.
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Alterations in Cerebrospinal Fluid Proteins in a Presymptomatic Primary Glioma Model
Whitin, J. C., Jang, T., Merchant, M., Yu, T. Ts., Lau, K., & Recht, L. (2012). Alterations in Cerebrospinal Fluid Proteins in a Presymptomatic Primary Glioma Model. PLOS ONE, 7(11).
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Metabolite kinetics in C6 rat glioma model using magnetic resonance spectroscopic imaging of hyperpolarized [1-13C]pyruvate
Park, J. M., Josan, S., Jang, T., Merchant, M., Yen, Y.-F., & Mayer, D. (2012). Metabolite kinetics in C6 rat glioma model using magnetic resonance spectroscopic imaging of hyperpolarized [1-13C]pyruvate. MAGNETIC RESONANCE IN MEDICINE, 68(6), 1886-1893.
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Preliminary use of differential scanning calorimetry of cerebrospinal fluid for the diagnosis of glioblastoma multiforme
Chagovetz, A. A., Jensen, R. L., Recht, L., Glantz, M., & Chagovetz, A. M. (2011). Preliminary use of differential scanning calorimetry of cerebrospinal fluid for the diagnosis of glioblastoma multiforme. JOURNAL OF NEURO-ONCOLOGY, 105(3), 499-506.
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Chemerin158K Protein Is the Dominant Chemerin Isoform in Synovial and Cerebrospinal Fluids but Not in Plasma
Zhao, L., Yamaguchi, Y., Sharif, S., Du, X.-Y., Song, J. J., & Leung, L. Lk. (2011). Chemerin158K Protein Is the Dominant Chemerin Isoform in Synovial and Cerebrospinal Fluids but Not in Plasma. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(45), 39520-39527.
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Treatment and Prophylaxis of Hematologic Malignancy in the Central Nervous System
Nagpal, S., & Recht, L. (2011). Treatment and Prophylaxis of Hematologic Malignancy in the Central Nervous System. CURRENT TREATMENT OPTIONS IN NEUROLOGY, 13(4), 400-412.
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5 '-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat
Jang, T., Calaoagan, J. M., Kwon, E., Samuelsson, S., Recht, L., & Laderoute, K. R. (2011). 5 '-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat. INTERNATIONAL JOURNAL OF CANCER, 128(9), 2230-2239.
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Central Nervous System Cancers
Brem, S. S., Bierman, P. J., Brem, H., Butowski, N., Chamberlain, M. C., & Wen, P. Y. (2011). Central Nervous System Cancers. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 9(4), 352-400.
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Time-lapse imaging of disease progression in deep brain areas using fluorescence microendoscopy
Barretto, R. Pj., Ko, T. H., Jung, J. C., Wang, T. J., Capps, G., & Schnitzer, M. J. (2011). Time-lapse imaging of disease progression in deep brain areas using fluorescence microendoscopy. NATURE MEDICINE, 17(2), 223-U120.
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Bevacizumab improves quality of life in patients with recurrent glioblastoma.
Nagpal, S., Harsh, G., & Recht, L. (2011). Bevacizumab improves quality of life in patients with recurrent glioblastoma. Chemotherapy research and practice, 2011, 602812-?.
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VERUBULIN HYDROCHLORIDE Apoptosis Inducer Vascular Disrupting Agent Oncolytic
Thomas, P., & Recht, L. (2010). VERUBULIN HYDROCHLORIDE Apoptosis Inducer Vascular Disrupting Agent Oncolytic. DRUGS OF THE FUTURE, 35(12), 993-997.
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Treatment and Prevention of Secondary CNS Lymphoma
Nagpal, S., Glantz, M. J., & Recht, L. (2010). Treatment and Prevention of Secondary CNS Lymphoma. SEMINARS IN NEUROLOGY, 30(3), 263-272.
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Murine Embryonic Stem Cell-Derived Pyramidal Neurons Integrate into the Cerebral Cortex and Appropriately Project Axons to Subcortical Targets
Ideguchi, M., Palmer, T. D., Recht, L. D., & Weimann, J. M. (2010). Murine Embryonic Stem Cell-Derived Pyramidal Neurons Integrate into the Cerebral Cortex and Appropriately Project Axons to Subcortical Targets. JOURNAL OF NEUROSCIENCE, 30(3), 894-904.
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Gender Disparity in the Rate of Partner Abandonment in Patients With Serious Medical Illness
Glantz, M. J., Chamberlain, M. C., Liu, Q., Hsieh, C.-C., Edwards, K. R., & Recht, L. (2009). Gender Disparity in the Rate of Partner Abandonment in Patients With Serious Medical Illness. CANCER, 115(22), 5237-5242.
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Understanding the Origins of Gliomas and Developing Novel Therapies: Cerebrospinal Fluid and Subventricular Zone Interplay
Glantz, M., Kesari, S., Recht, L., Fleischhack, G., & Van Horn, A. (2009). Understanding the Origins of Gliomas and Developing Novel Therapies: Cerebrospinal Fluid and Subventricular Zone Interplay. SEMINARS IN ONCOLOGY, 36(4), S17-S24.
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MOTEXAFIN GADOLINIUM COMBINED WITH PROMPT WHOLE BRAIN RADIOTHERAPY PROLONGS TIME TO NEUROLOGIC PROGRESSION IN NON-SMALL-CELL LUNG CANCER PATIENTS WITH BRAIN METASTASES: RESULTS OF A PHASE III TRIAL
Mehta, M. P., Shapiro, W. R., Phan, S. C., Gervais, R., Carrie, C., & Renschler, M. F. (2009). MOTEXAFIN GADOLINIUM COMBINED WITH PROMPT WHOLE BRAIN RADIOTHERAPY PROLONGS TIME TO NEUROLOGIC PROGRESSION IN NON-SMALL-CELL LUNG CANCER PATIENTS WITH BRAIN METASTASES: RESULTS OF A PHASE III TRIAL. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 73(4), 1069-1076.
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EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors
Li, L., Dutra, A., Pak, E., Labrie, J. E., Gerstein, R. M., & Ross, A. H. (2009). EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors. NEURO-ONCOLOGY, 11(1), 9-21.
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Embryonic stem cell rescue of tremor and ataxia in myelin-deficient shiverer mice
Low, H. P., Greco, B., Tanahashi, Y., Gallant, J., Jones, S. N., & Schwartz, W. J. (2009). Embryonic stem cell rescue of tremor and ataxia in myelin-deficient shiverer mice. JOURNAL OF THE NEUROLOGICAL SCIENCES, 276(1-2), 133-137.
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A distinct phenotypic change in gliomas at the time of magnetic resonance imaging detection
Jang, T., Sathy, B., Hsu, Y.-H., Merchant, M., Recht, B., & Recht, L. (2008). A distinct phenotypic change in gliomas at the time of magnetic resonance imaging detection. JOURNAL OF NEUROSURGERY, 108(4), 782-790.
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Optimizing therapy for patients with brain metastases
Kuo, T., & Recht, L. (2006). Optimizing therapy for patients with brain metastases. SEMINARS IN ONCOLOGY, 33(3), 299-306.
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Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea
Jang, T. C., Savarese, T., Low, H. P., Kim, S., Vogel, H., & Recht, L. (2006). Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea. AMERICAN JOURNAL OF PATHOLOGY, 168(5), 1676-1685.
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Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappa B-mediated resistance to O-6-alkylating agents in human glioblastomas
Bredel, M., Bredel, C., Juric, D., Duran, G. E., Yu, R. X., & Sikic, B. I. (2006). Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappa B-mediated resistance to O-6-alkylating agents in human glioblastomas. JOURNAL OF CLINICAL ONCOLOGY, 24(2), 274-287.
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Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas
Bredel, M., Bredel, C., Juric, D., Harsh, G. R., Vogel, H., & Sikic, B. I. (2005). Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas. CANCER RESEARCH, 65(19), 8679-8689.
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High-resolution genome-wide mapping of genetic alterations in human glial brain tumors
Bredel, M., Bredel, C., Juric, D., Harsh, G. R., Vogel, H., & Sikic, B. I. (2005). High-resolution genome-wide mapping of genetic alterations in human glial brain tumors. CANCER RESEARCH, 65(10), 4088-4096.
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Amplification of whole tumor genomes and geneby-gene mapping of genomic aberrations from limited sources of fresh-frozen and paraffin-embedded DNA
Bredel, M., Bredel, C., Juric, D., Kim, Y., Vogel, H., & Sikic, B. I. (2005). Amplification of whole tumor genomes and geneby-gene mapping of genomic aberrations from limited sources of fresh-frozen and paraffin-embedded DNA. JOURNAL OF MOLECULAR DIAGNOSTICS, 7(2), 171-182.
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Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure
Savarese, T. M., Jang, T., Low, H. P., Salmonsen, R., Litofsky, N. S., & Recht, L. D. (2005). Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure. JOURNAL OF NEUROSURGERY, 102(1), 98-108.
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Prevention and treatment of central nervous system involvement by non-Hodgkin's lymphoma: A review of the literature
Colocci, N., Glantz, M., & Recht, L. (2004). Prevention and treatment of central nervous system involvement by non-Hodgkin's lymphoma: A review of the literature. SEMINARS IN NEUROLOGY, 24(4), 395-404.
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Treatment of neoplastic meningitis: what is the standard of care?
Recht, L., & Phuphanich, S. (2004). Treatment of neoplastic meningitis: what is the standard of care?. Expert review of neurotherapeutics, 4(4), S11-7.
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Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis
Jang, T. C., Litofsky, N. S., Smith, T. W., Ross, A. H., & Recht, L. D. (2004). Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis. NEUROBIOLOGY OF DISEASE, 15(3), 544-552.
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Differentiation prevents assessment of neural stem cell pluripotency after blastocyst injection
Greco, B., Low, H. P., Johnson, E. C., Salmonsen, R. A., Gallant, J., & Recht, L. D. (2004). Differentiation prevents assessment of neural stem cell pluripotency after blastocyst injection. STEM CELLS, 22(4), 600-608.
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Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
Patient Comments
Patients comments are gathered from our Patient Satisfaction Survey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
SHC Patient, Jul 2015
The best medical care I could have expected. Dr. Recht also called, in a radiation oncologist to do a preliminary eval. which resulted in updated MRI needed ASAP.
SHC Patient, Jun 2015
Dr. Recht & his entire staff are terrific.
SHC Patient, Apr 2015
I am very happy with Dr. Recht and couldn't ask for a better oncologist.
SHC Patient, Mar 2015
Medication called in to pharmacy with incorrect instructions. Chemo cycle was stopped without telling me (I had asked if it could be temporarily stepped) with no further discussion (found out a week later).
SHC Patient, Feb 2015
When I go there I know every thing is going to be fine.
SHC Patient, Feb 2015
All experiences were good.
SHC Patient, Dec 2014
Dr. Recht is compassionate, kind, informative & reassuring I have the highest confidence in being his patient.
SHC Patient, Nov 2014
Very good.
SHC Patient, Nov 2014
Excellent!
SHC Patient, Aug 2014
Somewhat good.
SHC Patient, Apr 2014
Dr. Recht is very personable & relaxed. At same time professional & knowledgeable. Spends appropriate amt of time.
SHC Patient, Jul 2015
The best medical care I could have expected. Dr. Recht also called, in a radiation oncologist to do a preliminary eval. which resulted in updated MRI needed ASAP.
SHC Patient, Jun 2015
Dr. Recht & his entire staff are terrific.
SHC Patient, Apr 2015
I am very happy with Dr. Recht and couldn't ask for a better oncologist.
SHC Patient, Mar 2015
Medication called in to pharmacy with incorrect instructions. Chemo cycle was stopped without telling me (I had asked if it could be temporarily stepped) with no further discussion (found out a week later).
SHC Patient, Feb 2015
When I go there I know every thing is going to be fine.
SHC Patient, Feb 2015
All experiences were good.
SHC Patient, Dec 2014
Dr. Recht is compassionate, kind, informative & reassuring I have the highest confidence in being his patient.
SHC Patient, Nov 2014
Very good.
SHC Patient, Nov 2014
Excellent!
SHC Patient, Aug 2014
Somewhat good.
SHC Patient, Apr 2014
Dr. Recht is very personable & relaxed. At same time professional & knowledgeable. Spends appropriate amt of time.