Joshua M. Spin

Publications

• MicroRNAs in Abdominal Aortic Aneurysm
  Adam, M., Raaz, U., Spin, J. M., & Tsao, P. S. (2015). MicroRNAs in Abdominal Aortic Aneurysm. CURRENT VASCULAR PHARMACOLOGY, 13(3), 280-290.
• Battle of the bulge: miR-195 versus miR-29b in aortic aneurysm.
  Spin, J. M., & Tsao, P. S. (2014). Battle of the bulge: miR-195 versus miR-29b in aortic aneurysm. Circulation research, 115(10), 812-813.
• New ways to dismantle a ticking time bomb: microRNA 712/205 and abdominal aortic aneurysm development.
  Maegdefessel, L., Spin, J. M., & Tsao, P. S. (2014). New ways to dismantle a ticking time bomb: microRNA 712/205 and abdominal aortic aneurysm development. Arteriosclerosis, thrombosis, and vascular biology, 34(7), 1339-1340.
• Dichloroacetate prevents restenosis in preclinical animal models of vessel injury. Deuse, T., Hua, X., Wang, D., Maegdefessel, L., Heeren, J., & Schrepfer, S. (2014). Dichloroacetate prevents restenosis in preclinical animal models of vessel injury. Nature, 509(7502), 641-644.
  
• Hemodynamic Regulation of Reactive Oxygen Species: Implications for Vascular Diseases Raaz, U., Toh, R., Maegdefessel, L., Adam, M., Nakagami, F., & Tsao, P. S. (2014). Hemodynamic Regulation of Reactive Oxygen Species: Implications for Vascular Diseases. ANTIOXIDANTS & REDOX SIGNALING, 20(6), 914-928.
  
• Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse. Hennigs, J. K., Müller, J., Adam, M., Spin, J. M., Riedel, E., & Minner, S. (2014). Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse. PloS one, 9(7).
  
• Micromanaging Abdominal Aortic Aneurysms Maegdefessel, L., Spin, J. M., Adam, M., Raaz, U., Toh, R., & Tsao, P. S. (2013). Micromanaging Abdominal Aortic Aneurysms. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 14(7), 14374-14394.
  
• MicroRNA-24 controls abdominal aortic aneurysm development through regulation of YKL-40 Maegdefessel, L., Raaz, U., Adam, M., Spin, J., Eriksson, P., & Tsao, P. (2013). MicroRNA-24 controls abdominal aortic aneurysm development through regulation of YKL-40. INTERNIST, 54, 10-10.
  
• Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation. Leeper, N. J., Raiesdana, A., Kojima, Y., Kundu, R. K., Cheng, H., & Quertermous, T. (2013). Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation. Arteriosclerosis, thrombosis, and vascular biology, 33(1), e1-e10.
  
• Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling Spin, J. M., Maegdefessel, L., & Tsao, P. S. (2012). Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling. CARDIOVASCULAR RESEARCH, 95(2), 147-155.
  
• MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion Maegdefessel, L., Azuma, J., Toh, R., Deng, A., Merk, D. R., & Tsao, P. S. (2012). MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion. SCIENCE TRANSLATIONAL MEDICINE, 4(122).
  
• Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development Maegdefessel, L., Azuma, J., Toh, R., Merk, D. R., Deng, A., & Tsao, P. S. (2012). Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development. JOURNAL OF CLINICAL INVESTIGATION, 122(2), 497-506.
  
• miR-29b Participates in Early Aneurysm Development in Marfan Syndrome Merk, D. R., Chin, J. T., Dake, B. A., Maegdefessel, L., Miller, M. O., & Fischbein, M. P. (2012). miR-29b Participates in Early Aneurysm Development in Marfan Syndrome. CIRCULATION RESEARCH, 110(2), 312-?.
  
• In Vivo Functional and Transcriptional Profiling of Bone Marrow Stem Cells After Transplantation Into Ischemic Myocardium Sheikh, A. Y., Huber, B. C., Narsinh, K. H., Spin, J. M., van der Bogt, K., & Wu, J. C. (2012). In Vivo Functional and Transcriptional Profiling of Bone Marrow Stem Cells After Transplantation Into Ischemic Myocardium. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(1), 92-102.
  
• Microrna-21 Regulates Expansion of Abdominal Aortic Aneurysms Through the PTEN/PI3K/AKT Pathway Maegdefessel, L., Azuma, J., Deng, A., Toh, R. M., Merk, D. R., & Tsao, P. S. (2011). Microrna-21 Regulates Expansion of Abdominal Aortic Aneurysms Through the PTEN/PI3K/AKT Pathway. CIRCULATION, 124(21).
  
• Nicotine-Augmented Abdominal Aortic Aneurysms are Regulated by MicroRNA-29b Maegdefessel, L., Azuma, J., Merk, D. R., Toh, R. M., Deng, A., & Tsao, P. S. (2011). Nicotine-Augmented Abdominal Aortic Aneurysms are Regulated by MicroRNA-29b. CIRCULATION, 124(21).
  
• Cardiac pressure overload hypertrophy is differentially regulated by beta-adrenergic receptor subtypes Zhao, M., Fajardo, G., Urashima, T., Spin, J. M., Poorfarahani, S., & Bernstein, D. (2011). Cardiac pressure overload hypertrophy is differentially regulated by beta-adrenergic receptor subtypes. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 301(4), H1461-H1470.
  
• Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm Spin, J. M., Hsu, M., Azuma, J., Tedesco, M. M., Deng, A., & Tsao, P. S. (2011). Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm. PHYSIOLOGICAL GENOMICS, 43(17), 993-1003.
  
• MicroRNA-26a Is a Novel Regulator of Vascular Smooth Muscle Cell Function Leeper, N. J., Raiesdana, A., Kojima, Y., Chun, H. J., Azuma, J., & Spin, J. M. (2011). MicroRNA-26a Is a Novel Regulator of Vascular Smooth Muscle Cell Function. JOURNAL OF CELLULAR PHYSIOLOGY, 226(4), 1035-1043.
  
• Gene Mutations and Familial Thoracic Aortic Aneurysms A Walk on the Mild Side Spin, J. M. (2011). Gene Mutations and Familial Thoracic Aortic Aneurysms A Walk on the Mild Side. CIRCULATION-CARDIOVASCULAR GENETICS, 4(1), 4-6.
  
• Chromatin Remodeling Pathways in Smooth Muscle Cell Differentiation, and Evidence for an Integral Role for p300 Spin, J. M., Quertermous, T., & Tsao, P. S. (2010). Chromatin Remodeling Pathways in Smooth Muscle Cell Differentiation, and Evidence for an Integral Role for p300. PLOS ONE, 5(12).
  
• Nicotine Accelerates the Expansion of Abdominal Aortic Aneurysms in Mice; A Potential Role for miR-21 and miR-26a Maegdefessel, L., Azuma, J., Spin, J. M., Deng, A., McConnell, M. V., & Tsao, P. S. (2010). Nicotine Accelerates the Expansion of Abdominal Aortic Aneurysms in Mice; A Potential Role for miR-21 and miR-26a. CIRCULATION, 122(21).
  
• Microarray Analysis Identifies miRNA-26a as a Regulator of Vascular Smooth Muscle Cell Phenotypic Modulation Leeper, N. J., Raiesdana, A., Kojima, Y., Chun, H. J., Azuma, J., & Spin, J. M. (2010). Microarray Analysis Identifies miRNA-26a as a Regulator of Vascular Smooth Muscle Cell Phenotypic Modulation. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 30(11), E244-E244.
  
• New options with dabigatran etexilate in anticoagulant therapy. Maegdefessel, L., Spin, J. M., Azuma, J., & Tsao, P. S. (2010). New options with dabigatran etexilate in anticoagulant therapy. Vascular health and risk management, 6, 339-349.
  
• Analysis of In Situ and Ex Vivo Vascular Endothelial Growth Factor Receptor Expression During Experimental Aortic Aneurysm Progression Tedesco, M. M., Terashima, M., Blankenberg, F. G., Levashova, Z., Spin, J. M., & Dalman, R. L. (2009). Analysis of In Situ and Ex Vivo Vascular Endothelial Growth Factor Receptor Expression During Experimental Aortic Aneurysm Progression. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 29(10), 1452-?.
  
• Frontiers in nephrology: Genomic approaches to understanding the molecular basis of atherosclerosis Ashley, E. A., Spin, J. M., Tabibiazar, R., & Quertermous, T. (2007). Frontiers in nephrology: Genomic approaches to understanding the molecular basis of atherosclerosis. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 18(11), 2853-2862.
  
• Network analysis of human in-stent restenosis Ashley, E. A., Ferrara, R., King, J. Y., Vailaya, A., Kuchinsky, A., & Quertermous, T. (2006). Network analysis of human in-stent restenosis. CIRCULATION, 114(24), 2644-2654.
  
• Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes - Distinct responses to stimuli Deng, D. Xf., Spin, J. M., Tsalenko, A., Vailaya, A., Ben-Dor, A., & Quertermous, T. (2006). Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes - Distinct responses to stimuli. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 26(5), 1058-1065.
  
• Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation Wu, J. C., Spin, J. M., Cao, F., Lin, S. A., Xie, X. Y., & Quertermous, T. (2006). Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation. PHYSIOLOGICAL GENOMICS, 25(1), 29-38.
  
• Pathway analysis of coronary atherosclerosis King, J. Y., Ferrara, R., Tabibiazar, R., Spin, J. M., Chen, M. M., & Ashley, E. A. (2005). Pathway analysis of coronary atherosclerosis. PHYSIOLOGICAL GENOMICS, 23(1), 103-118.
  
• Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease Tabibiazar, R., Wagner, R. A., Ashley, E. A., King, J. Y., Ferrara, R., & Quertermous, T. (2005). Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease. PHYSIOLOGICAL GENOMICS, 22(2), 213-226.
  
• Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease Tabibiazar, R., Wagner, R. A., Spin, J. M., Ashley, E. A., Narasimhan, B., & Quertermous, T. (2005). Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 25(2), 302-308.
  
• Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation Spin, J. M., Nallamshetty, S., Tabibiazar, R., Ashley, E. A., King, J. Y., & Quertermous, T. (2004). Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation. PHYSIOLOGICAL GENOMICS, 19(3), 292-302.
  
• Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice Ishida, T., Choi, S. Sy., Kundu, R. K., Spin, J., Yamashita, T., & Quertermous, T. (2004). Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(43), 45085-45092.
  
• Treadmill scores in elderly men Lai, S., Kaykha, A., Yamazaki, T., Goldstein, M., Spin, J. M., & Froelicher, V. F. (2004). Treadmill scores in elderly men. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 43(4), 606-615.
  
• Retinal evaluation of patients on chronic amiodarone therapy Shaikh, S., Shaikh, N., Chun, S. H., Spin, J. M., Blumenkranz, M. S., & Marmor, M. F. (2003). Retinal evaluation of patients on chronic amiodarone therapy. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 23(3), 354-359.
  
• Is the Duke Treadmill Score appropriate in the elderly? Lai, S. R., Kaykha, A., Yamazaki, T., Spin, J., Goldstein, M., & Myers, J. (2003). Is the Duke Treadmill Score appropriate in the elderly?. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 51(4), S213-S213.
  
• Early use of statins in acute coronary syndromes. Spin, J. M., & Vagelos, R. H. (2003). Early use of statins in acute coronary syndromes. Current atherosclerosis reports, 5(1), 44-51.
  
• Early use of statins in acute coronary syndromes. Spin, J. M., & Vagelos, R. H. (2002). Early use of statins in acute coronary syndromes. Current cardiology reports, 4(4), 289-297.
  
• The prognostic value of exercise testing in elderly men Spin, J. M., PRAKASH, M., Froelicher, V. F., Partington, S., Marcus, R., & Myers, J. (2002). The prognostic value of exercise testing in elderly men. AMERICAN JOURNAL OF MEDICINE, 112(6), 453-459.
  
• Abnormal ECG after extensive maxillofacial surgery Spin, J., & Hancock, E. W. (1999). Abnormal ECG after extensive maxillofacial surgery. HOSPITAL PRACTICE, 34(11), 27-28.
  
• CRYOELECTRON MICROSCOPY OF LOW-DENSITY-LIPOPROTEIN IN VITREOUS ICE Spin, J. M., & Atkinson, D. (1995). CRYOELECTRON MICROSCOPY OF LOW-DENSITY-LIPOPROTEIN IN VITREOUS ICE. BIOPHYSICAL JOURNAL, 68(5), 2115-2123.