The NMS provides access to high-end, capital-intensive microscopy equipment that is often not available to individual labs.
Available Equipment
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two two-photon microscopes:
- an in vivo rig, and
- a slice rig;
- confocal microscopy with time-lapse and spectral unmixing capability
- conventional widefield fluorescence microscopy
Selected References
Versatile synthesis and rational design of caged morpholinos. Ouyang X, Shestopalov IA, Sinha S, Zheng G, Pitt CL, Li WH, Olson AJ, Chen JK J Am Chem Soc. 2009 Sep 23;131(37):13255-69. PubMedID: 19708646; PMCID: PMC2745229.
Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Yazawa M, Hsueh B, Jia X, Pasca AM, Bernstein JA, Hallmayer J, Dolmetsch RE. Nature. 2011 Mar 10;471(7337):230-4. Epub 2011 Feb 9. PubMedID: 21307850; PMCID: PMC3077925.
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Tang C, Lee AS, Volkmer JP, Sahoo D, Nag D, Mosley AR, Inlay MA, Ardehali R, Chavez SL, Pera RR, Behr B, Wu JC, Weissman IL, Drukker M. Nat Biotechnol. 2011 Aug 14;29(9):829-34. PubMedID: 21841799.
