Stanford Movement Disorders Center Clinical Trials
PARKINSON’S DISEASE
Development of Multimodal Imaging Biomarkers for Cognitive Dysfunction in Parkinson's Disease
Sponsor: The Michael J. Fox Foundation for Parkinson’s disease Research
PI: Kathleen Poston, M.D., M.S.
Study status: Enrollment closed, study ongoing
Research coordinator: Taylor Hendershott
trhend15@stanford.edu (650) 723-0060
Structural Correlates of Cognitive and Motor Dysfunction in Parkinsonian Disorders
PI: Kathleen Poston, M.D., M.S.
Study Status: Enrollment closed, study ongoing
Research coordinator: Taylor Hendershott
trhend15@stanford.edu (650) 723-0060
Functional Networks in Parkinson's Disease - an fMRI Activation and Functional Connectivity Study
Sponsor: NIH/NINDS
PI: Kathleen Poston, M.D., M.S.
Study Status: Closed to enrollment, analysis ongoing
Research coordinator: Taylor Hendershott
trhend15@stanford.edu (650) 723-0060
A Phase 1/2 Trial Assessing the Safety and Efficacy of Bilateral Intraputaminal and Intranigral Administration of CERE-120 (Adeno-Associated Virus Serotype 2 [AAV2]-Neurturin [NTN]) in Subjects With Idiopathic Parkinson’s Disease
Clinical Trials Protocol #: NCT00400634
Sponsor: Sangamo Biosciences, Inc
Site PI: Kathleen Poston, M.D., M.S.
Study Status: Closed to enrollment, outcome published
Research coordinator: Taylor Hendershott
trhend15@stanford.edu (650) 723-0060
Neural Signatures of Tremor, Bradykinesia and Freezing in the Subthalamic Region in Parkinson’s Disease and their Acute and Long-Term Modulation by Subthalamic Deep Brain Stimulation
Clinical Trials Protocol #: NCT01990313
Sponsor: Medtronic
PI: Helen Bronte Stewart, M.D.
Study status: Open, enrollment by invitation only
Research coordinator: Emma Quinn
equinn@stanford.edu (650-855-4656)
Adaptive Closed Loop Neuromodulation and Neural Signatures of Parkinson's Disease (aDBS)
Clinical Trials Protocol #: NCT02384421
Sponsor: Medtronic, Michael J. Fox Foundation
PI: Helen Bronte Stewart, M.D.
Study status: Open, enrollment by invitation only
Research coordinator: Emma Quinn
equinn@stanford.edu (650-855-4656)
Frequency Effects of Deep Brain Stimulation on Movement in Parkinson’s Disease.
PI: Helen Bronte Stewart, M.D.
Study status: Open, enrollment by invitation only
Research coordinator: Emma Quinn
equinn@stanford.edu (650-855-4656)
Neurodegeneration and Brain Function in Aging with HIV and Parkinson's Disease
Sponsor: NIH/NINDS
Site PI: Helen Bronte-Stewart, M.D., M.S.
Study Status: Open, enrollment ongoing
Research coordinator: Talora Martin
talora@stanford.edu, (412) 841-0774
Healthy Brain Aging Study
Sponsor: NIH/NIA
PI: Victor Henderson, M.D. and Tony Wyss-Coray, Ph.D
Study Status: Open, enrollment ongoing
Research coordinator: Christina Wyss-Coray
ADRCstanford@stanford.edu (650) 721-2409
ATYPICAL PARKINSONISM (MSA, PSP, CBD, DLB)
Early Differential Diagnosis of Parkinsonism with Metabolic Imaging and Pattern Analysis
Sponsor: NIH/NINDS and The Michael J. Fox Foundation for Parkinson’s disease Research
Site PI: Kathleen Poston, M.D., M.S.
Study status: Open, enrollment ongoing.
Research coordinator: Taylor Hendershott
trhend15@stanford.edu (650) 723-0060
A 12-Week, Multicenter, Randomized, Parallel-Group Study to Assess the Safety, Tolerability, Pharmacokinetics, Biomarker Effects, Efficacy, and Effect on Microglia Activation, as Measured by Positron Emission Tomography, of AZD3241 in Subjects with Multiple System Atrophy
Clinical Trials #: NCT02388295
Sponsor: Astra Zeneca
PI: Kathleen Poston
Study Status: Open, enrollment ongoing
Research coordinator: Kara Richardson
kjr9@stanford.edu 650-736-6171
ESSENTIAL TREMOR
A pivotal study to evaluate the effectiveness and safety of ExAblate transcranial MRgFUS thalamotomy treatment of medication refractory essential tremor subjects.
Clinical Trials Protocol#: NCT01827904
Sponsor: Insightec
Site PI: Pejman Ghanouni, MD, PhD
Study status: Open, enrollment ongoing.
Research coordinator: Jennifer Marcellus
jmarcell@stanford.edu (650)497-5714